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Table 2 Acute kidney injury risk indicated by these biomarkers in septic patients analyzed by using logistic regression with generalized estimating equations

From: Diagnostic value of neutrophil gelatinase-associated lipocalin, cystatin C, and soluble triggering receptor expressed on myeloid cells-1 in critically ill patients with sepsis-associated acute kidney injury

Variable Crude: model 1 a Adjusted: model 2 b Adjusted: model 3 c
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
Plasma NGAL 1.013 (1.010-1.015) <0.001 1.012 (1.009-1.014) <0.001 1.013 (1.010-1.022) <0.001
Urine NGAL 1.030 (1.014-1.047) <0.001 1.029 (1.014-1.045) <0.001 1.027 (1.011-1.044) 0.001
Plasma Cys-Cd 1.003 (1.002-1.004) 0.001 1.003 (1.002-1.003) 0.001 1.003 (1.002-1.003) <0,001
Urine Cys-Cd 1.010 (1.005-1.014) <0.001 1.024 (1.018-1.038) <0.001 1.022 (1.008-1.035) 0.001
Plasma sTREM-1 1.029 (1.021-1.037) <0.001 1.023(1.016-1.031) <0.001 1.028(1.018-1.037) <0.001
Urine sTREM-1 1.038(1.019-1/057 <0.001 1.033(1.016-1.050 <0.001 1.031(1.009-1.053) 0.005
  1. aNot adjusted. bAdjusted for serum creatinine (SCr). cAdjusted for mean arterial pressure, Acute Physiology and Chronic Health Evaluation II scores, Sequential Organ Failure Assessment scores, and procalcitonin in addition to SCr. dOdds ratio (ORs) represent the increase in risk per 0.001 mg/L increase in cystatin C (Cys-C). CI, confidence interval; NGAL, neutrophil gelatinase-associated lipocalin; sTREM-1, soluble triggering receptor expressed on myeloid cells-1.