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Table 1 Baseline and ICU admission characteristics for patients surviving to ICU discharge

From: Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study

 

ICU-AW

No ICU-AW

P value

(N = 60)

(N = 73)

Patient characteristics

   

Age, mean ± SD

65 ± 16

59 ± 14

0.03

Female, n (%)

27 (45)

30 (41)

0.78

BMI (kg/m2), mean ± SD

26.8 ± 5.1

26.9 ± 5.2

0.86

BMI >30, n (%)

14 (23)

16 (22)

1.00

Pre-existing neuromuscular disorder, n (%)

3 (5)

1 (1)

0.33

Charlson co-morbidity index, median (IQR)

0 (0-1)

0 (0-2)

0.05

ICU admission characteristics

   

Admission type

   

  Medical, n (%)

34 (63)

41 (57)

0.99

  Surgical elective, n (%)

15 (21)

18 (24)

  Surgical emergency, n (%)

11 (16)

14 (19)

APACHE IV score, mean ± SD (2 missing)

81 ± 23

73 ± 28

0.10

CNS disorder as reason of admission, n (%)

1 (2)

0 (0)

0.45

Maximal SOFA score during admission, mean ± SD

12 ± 3

9 ± 4

<0.01

Sepsis during admission, n (%)

56 (93)

57 (78)

0.03

Severe sepsis during admission, n (%)

49 (82)

42 (58)

0.01

Septic shock during admission, n (%)

35 (58)

26 (36)

0.01

Renal replacement therapy during admission, n (%)

23 (38)

19 (26)

0.18

ARDS during admission, n (%)

28 (47)

32 (44)

0.88

Days with mechanical ventilation, median (IQR)

11 (6-17)

5 (4-7)

<0.01

Length of stay in ICU (days), median (IQR)

14 (9-20)

7 (5-10)

<0.01

Average MRC score, median (IQR)

2.8 (1.8-3.5)

4.7 (4-5)

n.a.

Post-ICU admission characteristics

   

Days free from hospital and alive at 3 months after ICU discharge, median (IQR)

57 (15-71)

75 (56-82)

<0.01

Discharge destination from index hospital if discharged alive

   

  Other hospital, n/total n (%)

22/53 (41)

14/71 (20)

0.01*

  Rehabilitation facility, n/total n (%)

14/53 (27)

4/71 (6)

  Home, n/total n (%)

17/53 (32)

53/71 (76)

  1. APACHE IV, Acute Physiology and Chronic Health Evaluation IV; ARDS, Acute Respiratory Distress Syndrome; BMI, body mass index; CNS, central nervous system; ICU-AW, ICU-acquired weakness; IQR, interquartile range; MRC, muscle strength as assessed with Medical Research Council scale; SD, standard deviation; SOFA, Sequential Organ Failure Assessment score; n.a., not applicable; *, overall test for differences between groups.