|
Sensitivity
|
Specificity
|
Positive predictive value
|
Negative predictive value
|
Kappa (SD)
|
Overall agreement (%)
|
---|
|
%
|
(95% CI)
|
%
|
(95% CI)
|
%
|
(95% CI)
|
%
|
(95% CI)
| | |
---|
ALTOS Data
|
6 Months
|
MMSE <24
|
24
|
(14–35)
|
93
|
(87–97)
|
67
|
(45–84)
|
67
|
(59–74)
|
0.19 (0.06)
|
67
|
12 Months
|
MMSE <24
|
30
|
(17–46)
|
97
|
(92–99)
|
76
|
(50–93)
|
81
|
(74–87)
|
0.34 (0.07)
|
80
|
ABC Data
|
Discharge
|
MMSE <24
|
37
|
(26–49)
|
100
|
(59–100)
|
100
|
(87–100)
|
13
|
(6–26)
|
0.09 (0.05)
|
42
|
3 Months
|
MMSE <24
|
22
|
(12–34)
|
100
|
(79–100)
|
100
|
(75–100)
|
25
|
(15–38)
|
0.10 (0.05)
|
38
|
12 Months
|
MMSE <24
|
19
|
(8–35)
|
100
|
(78–100)
|
100
|
(59–100)
|
33
|
(20–49)
|
0.12 (0.07)
|
42
|
- MMSE, mini-mental status examination; SD standard deviation.
- Impairment on neuropsychological test battery = any battery test ≤2 SD or 2+ tests ≤ 1.5 SD.
- For ALTOS study data: At 6 months: N = 181; True positives = 9%; False positives = 4%; True negatives = 58%; False negatives = 29%. At 12 months: N = 174; True positives = 7%; False positives = 2%; True negatives = 73%; False negatives = 17%.
- For ABC study data: At discharge: N = 78; True positives = 33%; False positives = 0%; True negatives = 9%; False negatives = 58%. At 3 months: N = 76; True positives =17%; False positives = 0%; True negatives = 21%; False negatives = 62%. At 12 months: N = 52; True positives = 13%; False positives = 0%; True negatives = 29%; False negatives = 58%.