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Table 2 Overall cognitive impairment at discharge, 3, 6 and 12 months for MMSE versus neuropsychological test battery

From: Cognitive screening among acute respiratory failure survivors: a cross-sectional evaluation of the Mini-Mental State Examination

 

Sensitivity

Specificity

Positive predictive value

Negative predictive value

Kappa (SD)

Overall agreement (%)

 

%

(95% CI)

%

(95% CI)

%

(95% CI)

%

(95% CI)

  

ALTOS Data

6 Months

MMSE <24

24

(14–35)

93

(87–97)

67

(45–84)

67

(59–74)

0.19 (0.06)

67

12 Months

MMSE <24

30

(17–46)

97

(92–99)

76

(50–93)

81

(74–87)

0.34 (0.07)

80

ABC Data

Discharge

MMSE <24

37

(26–49)

100

(59–100)

100

(87–100)

13

(6–26)

0.09 (0.05)

42

3 Months

MMSE <24

22

(12–34)

100

(79–100)

100

(75–100)

25

(15–38)

0.10 (0.05)

38

12 Months

MMSE <24

19

(8–35)

100

(78–100)

100

(59–100)

33

(20–49)

0.12 (0.07)

42

  1. MMSE, mini-mental status examination; SD standard deviation.
  2. Impairment on neuropsychological test battery = any battery test ≤2 SD or 2+ tests ≤ 1.5 SD.
  3. For ALTOS study data: At 6 months: N = 181; True positives = 9%; False positives = 4%; True negatives = 58%; False negatives = 29%. At 12 months: N = 174; True positives = 7%; False positives = 2%; True negatives = 73%; False negatives = 17%.
  4. For ABC study data: At discharge: N = 78; True positives = 33%; False positives = 0%; True negatives = 9%; False negatives = 58%. At 3 months: N = 76; True positives =17%; False positives = 0%; True negatives = 21%; False negatives = 62%. At 12 months: N = 52; True positives = 13%; False positives = 0%; True negatives = 29%; False negatives = 58%.
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Critical Care

ISSN: 1364-8535