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Table 1 Fatty acids in the plasma and monocyte membranes

From: Immunomodulation by lipid emulsions in pulmonary inflammation: a randomized controlled trial

   Time, hours
  Group 0 8 24
Free fatty acid, μmol/l     
AA NaCl 4.0 ± 0.6 3.3 ± 0.3 4.9 ± 1.0
  SO 4.0 ± 0.6 4.0 ± 0.7 4.6 ± 1.3
  FO 4.3 ± 0.5 4.2 ± 0.8 5.0 ± 1.1
EPA NaCl 0.6 ± 0.1 0.3 ± 0.0 0.4 ± 0.1
  SO 0.6 ± 0.1 0.5 ± 0.1 0.7 ± 0.2
  FO 0.7 ± 0.2 3.4 ± 0.8ab 2.5 ± 0.4ab
DHA NaCl 0.8 ± 0.1 0.6± 0.2 0.9 ± 0.2
  SO 0.8 ± 0.1 0.9 ± 0.1 1.0 ± 0.2
  FO 0.9 ± 0.1 2.2 ± 0.3a b 3.0 ± 0.7a b
Sum NaCl 335.1 ± 50.2 336.8 ± 42.4 408.6 ± 74.3
  SO 346.0 ± 53.9 372.1 ± 42.1 366.5 ± 59.8
  FO 377.4 ± 44.1 250.1 ± 29.8 348.3 ± 83.0
Membrane fatty acid. %     
AA NaCl 19.7 ± 0.5 19.2 ± 0.6 18.5 ± 0.5
  SO 19.4 ± 0.4 18.0 ± 0.8 20.0 ± 0.3
  FO 19.4 ± 0.6 17.1 ± 0.8a 17.4 ± 1.1a
EPA NaCl 0.2 ± 0.0 0.1 ± 0.0 0.1 ± 0.0
  SO 0.2 ± 0.0 0.1 ± 0.0 0.2 ± 0.0
  FO 0.2 ± 0.0 1.9 ± 0.2a b 1.3 ± 0.1a b
DHA NaCl 2.6 ± 0.1 2.4 ± 0.3 2.3 ± 0.2
  SO 2.9 ± 0.2 2.5 ± 0.3 2.8 ± 0.4
  FO 3.1 ± 0.2 4.8 ± 0.2a b 4.7 ± 0.4a b
  1. Plasma and isolated monocytes originated from volunteers receiving fish oil (FO)- or soybean oil (SO)-based lipid infusion, or normal saline (NaCl). Free fatty acids (AA, arachidonic acid; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid) and membrane fatty acids were determined by gas chromatography: a P <0.05 versus baseline; b P <0.05 versus SO and NaCl. Data are presented as mean +/- standard error of the mean; n =12 for baseline and n = 5 – 6 for later time points.