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Table 1 Trends in variables during first 7 days of intensive care unit staya

From: Association between trends in clinical variables and outcome in intensive care patients with faecal peritonitis: analysis of the GenOSept cohort

  Day 1 Day 7
Characteristics N n or median % or IQR N n or median % or IQR
Organ failure and support       
  ARF 974 283 29.1% 659 159 24.1%
  RRT 974 115 11.8% 659 104 15.8%
  Ventilatory support 974 743 76.3% 657 413 62.9%
  Inotrope/vasopressor useb 974    660   
   None   267 27.4%   434 65.8%
   A   33 3.4%   36 5.5%
   B   169 17.4%   105 15.9%
   C   505 51.9%   85 12.9%
  SOFA 974 7 5 to 10 659 5 2 to 8
   GCS SOFA 974 0 0 to 1 674 0 0 to 1
   CVS SOFA 974 4 1 to 4 671 1 0 to 3
   Coagulation SOFA 974 0 0 to 1 674 0 0 to 1
   Respiratory SOFA 974 2 2 to 3 659 2 1 to 3
   Renal SOFA 974 1 0 to 2 674 0 0 to 1
   Bilirubin SOFA 974 0 0 to 1 674 0 0 to 0
Laboratory variables       
  Serum bicarbonate 893 21 18 to 24 580 26 23 to 29.1
  paO2 (kPa) 945 11.3 9.6 to 13.9 590 10.8 9.2 to 13.6
  paCO2 (kPa) 938 5.2 4.6 to 6 535 5.2 4.7 to 6
  Highest creatinine (μmol/L) 974 106.6 76 to 160 654 81.5 53.9 to 132
  Lowest creatinine (μmol/L) 974 100 70 to 144 642 81.5 54 to 130
  Highest WCC (10−9/L) 974 12 7.1 to 18 643 15.3 11 to 20.4
  Lowest WCC (10−9/L) 974 9.4 4.6 to 15 643 15 10.5 to 20
  Lowest platelets (10−9/L) 974 212.5 145 to 300 640 234.5 132 to 352.5
  Highest bilirubin (mmol/L) 974 13 8 to 22 650 10 5 to 19
  Highest urea (mmol/L) 908 11 6.4 to 17.1 607 11.6 7.2 to 20.8
Chest radiography findings       
  Localised infiltrates 973 115 11.8% 672 68 10.1%
  Lobar infiltrates 973 61 6.3% 672 32 4.8%
  Diffuse bilateral infiltrates 973 148 15.2% 672 109 16.2%
Physiological parameters       
  Highest temperature (°C) 974 37.7 37 to 38.3 656 37.4 37 to 38
  Lowest temperature (°C) 974 36.2 35.7 to 36.9 656 36.5 36 to 37
  Highest SBP (mmHg) 974 140 125 to 155 655 150 135 to 170
  Lowest SBP (mmHg) 972 90 80 to 100 655 108 95 to 120
  Highest MAP (mmHg) 972 91 82 to 103 649 98 89 to 110
  Lowest MAP (mmHg) 970 62 56 to 70 649 71 63 to 80
  Highest heart rate (bpm) 974 117 103 to 130 655 104 90 to 118
  Lowest heart rate (bpm) 971 85 73 to 99 655 80 70 to 90
  Respiratory rate (breaths/min) 966 18 14 to 24 638 20 16 to 27
  Urinary volume (ml/24 hr) 973 1,375 790 to 2,100 644 2,276.5 1,333.5 to 3,411.5
  paO2/FiO2 ratio (kPa) 942 27.8 19.6 to 37.7 573 30.7 23.1 to 39.2
  1. aARF, Acute renal failure; bpm, Beats per minute; CVS, Cardiovascular; GCS, Glasgow Coma Scale; IQR, Interquartile range; MAP, Mean arterial pressure; n, Absolute count; N, Number of non-missing observations; paCO2, Arterial partial pressure of carbon dioxide; paO2, Arterial partial pressure of oxygen; paO2/FiO2, Ratio of partial pressure of arterial oxygen to fraction of inspired oxygen; RRT, Renal replacement therapy; SBP, Systolic blood pressure; SOFA, Sequential Organ Failure Assessment; WCC, White cell count. bInotropic and vasopressor use is coded as follows: A = dopamine ≤5 μg/kg/min or dobutamine; B = dopamine >5 μg/kg/min or adrenaline/noradrenaline ≤0.1 μg/kg/min; C = dopamine >15 μg/kg/min or adrenaline/noradrenaline >0.1 μg/kg/min.