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Table 5 Cox proportional hazards model of significant predictors for in-hospital mortality

From: An international multicenter retrospective study of Pseudomonas aeruginosa nosocomial pneumonia: impact of multidrug resistance

Variable

Hazards ratio (95% CI)

P -value

Heart failure

1.88 (1.39, 2.52)

<0.001

Age (increasing increments of 1 year)

1.02 (1.01, 1.03)

0.001

Country of origin, Germany

3.05 (1.87, 4.96)

<0.001

Country of origin, Italy

2.38 (1.41, 4.02)

0.001

Country of origin, Spain

1.91 (1.16, 3.14)

0.011

Mechanical ventilation

1.88 (1.02, 3.48)

0.044

Bacteremia

1.67 (1.20, 2.31)

0.002

Multidrug resistance

1.39 (1.05, 1.83)

0.021

No vasopressors

0.61 (0.43, 0.87)

0.006

Healthcare associated pneumonia

0.50 (0.35, 0.73)

<0.001

  1. Variables excluded from the model for co-linearity: aminoglycoside resistance, carbapenem resistance, fluoroquinolone resistance, penicillin-β-lactamase inhibitor resistance (co-linear with multidrug resistance); country of origin - United States (co-linear with France, Germany, Italy, and Spain). Variables included but not retained in the model at P <0.05: ICU admission, chronic kidney disease, chronic liver disease, country of origin - France.