Table 1 Clinical and epidemiological characteristics of multidrug (MDR) and non-multidrug resistant patients with Pseudomonas aeruginosa pneumonia
Characteristic | Percent missing (of total 740) | MDR N = 226 | Non-MDR N = 514 | P -value |
|---|---|---|---|---|
Age, years, mean ± SD | 0.5%a | 53.5 ± 17.5 | 62.1 ± 15.5 | <0.001 |
Male | 0% | 142 (62.8%) | 361 (70.2%) | 0.047 |
Location prior to admission | 1.1% | Â | Â | Â |
 Community |  | 101 (44.7%) | 286 (55.6%) | 0.006 |
 Skilled nursing facility |  | 17 (7.5%) | 37 (7.2%) | 0.876 |
 Long-term care facility |  | 7 (3.1%) | 20 (3.9%) | 0.596 |
 Assisted living |  | 4 (1.8%) | 3 (0.6%) | 0.125 |
 Inpatient rehabilitation |  | 27 (11.9%) | 20 (3.9%) | <0.001 |
 Other |  | 66 (29.2%) | 144 (28.0%) | 0.741 |
Past medical history | Â | Â | Â | Â |
 Hospitalized in the previous 6 months | 13.1% | 126 (60.6%) | 245 (56.3%) | 0.307 |
 Antibiotics in the previous 30 days | 27.6% | 100 (57.5%) | 163 (45.0%) | 0.007 |
 Heart failure | 9.6% | 49 (23.2%) | 131 (28.6%) | 0.145 |
 Chronic obstructive pulmonary disease | 9.2% | 102 (48.8%) | 173 (37.4%) | 0.005 |
 Diabetes mellitus | 8.6% | 79 (37.8%) | 137 (29.3%) | 0.029 |
 Chronic kidney disease | 9.3% | 55 (26.3%) | 118 (25.5%) | 0.832 |
 Chronic liver disease | 11.9% | 38 (18.5%) | 70 (15.7%) | 0.359 |
 Hematologic malignancy | 9.9% | 20 (9.4%) | 40 (8.8%) | 0.807 |
 Solid tumor | 10.3% | 18 (8.7%) | 81 (17.7%) | 0.002 |
 HIV/AIDS | 10.5% | 3 (1.5%) | 6 (1.3%) | 0.885 |
 Dementia | 12.6% | 6 (3.0%) | 36 (8.1%) | 0.015 |
Charlson score, mean ± SD | 2.6% | 3.1 ± 2.6 | 3.0 ± 2.6 | 0.869 |
Pneumonia category | 0% | Â | Â | Â |
 Community-onset, healthcare-associated |  | 74 (32.7%) | 167 (32.5%) | 0.946 |
 Hospital-onset |  | 152 (67.2%) | 347 (67.5%) | 0.946 |
  Hospital-acquired |  | 50 (22.1%) | 112 (21.8%) | 0.919 |
  Ventilator-associated |  | 102 (45.1%) | 235 (45.7%) | 0.883 |
ICU admission | 0% | 180 (79.6%) | 367 (71.4%) | 0.019 |
Length of ICU stay, days, median (IQR) | 0% | 18.9 (11.4, 32.5) | 16.1 (8.7, 29.1) | 0.058 |
Mechanical ventilation | 0% | 197 (87.2%) | 440 (85.6%) | 0.571 |
Length of mechanical ventilation, days, median (IQR) | 0% | 17.0 (9.1, 34.1) | 13.1 (6.5, 26.0) | 0.006 |
Vasopressor administration | 0% | 146 (64.6%) | 308 (59.9%) | 0.229 |
Bacteremia | 0% | 53 (23.5%) | 128 (24.9%) | 0.672 |
Inappropriate initial antibiotic therapy | 1.5% | 83 (37.9%) | 98 (19.2%) | <0.001 |
In-hospital mortality | 0% | 101 (44.7%) | 163 (31.7%) | 0.001 |
Length of hospital stay, days, median (IQR) | 0% | 27.0 (14.0, 56.3) | 25.0 (13.0, 46.0) | 0.090 |