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Table 3 Comparison of variables related to weaning process

From: Management and outcome of mechanically ventilated patients after cardiac arrest

 

Cohort 1998

Cohort 2004

Cohort 2010

P

(N = 100)

(N = 239)

(N = 473)

Accidental extubation, n (%)a

3 (3)

6 (3)

29 (6)

0.062

Reintubation, %

67

33

14

0.074

Patients weaned and scheduled extubated, n (%)

47 (47)

104 (44)

211 (45)

0.856

Method for first attempt

    

Spontaneous breathing trial, n (%)

33/47 (70)

71/104 (68)

154/211(73)

0.675

 T-piece, %

48.5

38

36

0.022

 CPAP, %

6

34

24

 Low level pressure support, %

42

27

40

 Other, %

3

1

0

Gradual reduction of support, n (%)

14/47 (30)

33/104 (32)

57/211 (27)

0.675

 Pressure support, %

14

61

89

<0.001

 SIMV, %

29

6

0

 SIMV-PS, %

50

18

9

 Other, %

7

15

2

Failure of first weaning attempt, n (%)

24/47 (51)

45/104 (43)

95/211 (45)

0.667

Method for second attempt

    

Spontaneous breathing trial, n (%)

21 (87.5)

10 (22)

59 (62)

<0.001

 T-piece, %

67

40

36

0.049

 CPAP, %

5

20

34

 Low level pressure support, %

24

40

30

 Other, %

5

0

0

Gradual reduction of support, n (%)

3 (12.5)

35 (78)

36 (38)

<0.001

 Pressure support, %

0

66

94

<0.001

 SIMV, %

0

6

0

 SIMV-PS, %

100

14

3

 Other, %

0

14

3

Reintubation after scheduled extubation, %

11

7

11

0.426

Tracheotomy, n (%)a

12 (12)

30 (13)

66 (14.5)

0.758

  1. aExcluded patients with prior tracheostomy: 1 patient in 1998, 7 patients in 2004 and 18 patients in 2010.
  2. SIMV, synchronized intermittent mandatory ventilation; SIMV-PS, synchronized intermittent mandatory ventilation with pressure support; PSV, pressure support ventilation; CPAP, continuous positive airway pressure.