Evolution of chronic renal impairment and long-term mortality after de novo acute kidney injury in the critically ill; a Swedish multi-centre cohort study

Table 4 Multivariate poisson regression for secondary outcomes

	Multivariate poisson regression analysis
Group	Patients, number	Events, number	Person-years	IR event/person-year (95% CI)	Crude IRR (95% CI)	Adjusted IRR^a (95% CI)
A. CKD
No AKI	92,509	649	1.7 × 10⁵	0.0038 (0.0035, 0.0041)	1	1
AKI	5,273	193	4.9 × 10³	0.0340 (0.0341, 0.0452)	10.3 (8.8, 12.1)	7.6 (5.5, 10.4)
B. ESRD
No AKI	92,509	116	1.7 × 10⁵	0.0007 (0.0006, 0.0008)	1	1
AKI	5,273	65	5.2 × 10³	0.0125 (0.0098, 0.0160)	18.6 (13.7, 25.2)	22.5 (12.9, 39.1)

^aAdjusted for simplified applied physiology score version III, age, gender and diabetes. CKD, chronic kidney disease; ESRD, end-stage renal disease; AKI, acute kidney injury; IR, incidence rate; IRR, incidence rate ratio.

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