Figure 3
From: Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis
Delayed kallistatin administration attenuated liver injury, serum alanine transaminase (ALT) levels and liver tumor necrosis factor-α (TNF-α) expression in cecal ligation and puncture (CLP) mice. (A) H&E staining was performed on liver sections to examine liver histology (n = 4). Representative sections are shown at ×200 magnification. (B) Serum ALT levels and (C) liver TNF-α expression were significantly decreased in kallistatin-treated CLP mice (n = 3 to 4). Data are expressed as means ± SE. *P <0.05 versus sham group; # P <0.05 versus CLP control group.