Association between biomarkers of endothelial injury and hypocoagulability in patients with severe sepsis: a prospective study

Table 1 Baseline (inclusion) characteristics, endothelial-derived biomarker levels, thrombelastography, transfusions during ICU stay and outcome in 184 patients with severe sepsis

Data are presented as medians (IQR) or n (%). BUN, blood urea nitrogen; Emergency surgery, emergency surgery prior to ICU admission; FF MA, maximum amplitude in functional fibrinogen; FEU, fibrinogen equivalent units; FFP, fresh frozen plasma; Ly30, lysis 30 minutes after MA; Mortality; mortality of any cause; Owren type PT, reporting coagulation factor activity in percentage [41]; PAI-1, plasminogen activator inhibitor-1; R-time, reaction time; RBC, red blood cells; SAPS, simplified acute physiology score (calculated from 17 variables with higher scores indicating more severe disease, but without recording the cerebral component of the score); SBP, systolic blood pressure; SOFA, sequential organ failure assessment (sub-scores ranging from 0 to 4 for each of five components (circulation, lungs, liver, kidneys and coagulation, with aggregated scores ranging from 0 to 20, with higher scores indicating more severe organ failure); TEG MA, maximum amplitude in kaolin TEG; tPA, tissue-type plasminogen activator.

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