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Table 1 Comparison of demographic and clinical severity data between traumatic brain injury survivors and non-survivorsa

From: Serum substance P levels are associated with severity and mortality in patients with severe traumatic brain injury

 

Non-survivors (n =27)

Survivors (n =73)

P -value

Glasgow Coma Scale score

3 (3 to 6)

7 (6 to 8)

<0.001

APACHE II score

26 (25 to 32)

19 (17 to 23)

<0.001

Age (yr)

66 (45 to 76)

47 (32 to 67)

<0.001

Substance P (pg/ml)

420 (310 to 815)

250 (99 to 496)

0.002

CT findings

  

0.002

 Class I

0

0

 

 Class II

3 (11.1)

21 (28.8)

 

 Class III

5 (18.5)

13 (17.8)

 

 Class IV

6 (22.2)

10 (13.7)

 

 Class V

5 (18.5)

26 (35.6)

 

 Class VI

8 (29.6)

3 (4.1)

 

Female sex

11 (40.7)

12 (16.4)

0.02

Temperature (°C)

36.0 (35.0 to 37.0)

37.0 (35.6 to 37.3)

0.12

Sodium (mEq/L)

141 (135 to 149)

139 (138 to 142)

0.19

Platelets (*103/mm3)

215 (139 to 264)

182 (143 to 252)

0.48

PaO2 (mmHg)

141 (104 to 186)

151 (116 to 217)

0.34

PaO2/FiO2 ratio

190 (154 to 316)

336 (242 to 407)

0.11

Leukocytes (*103/mm3)

18.3 (10.7 to 23.9)

14.7 (10.2 to 19.3)

0.46

Lactic acid (mmol/L)

1.90 (1.15 to 4.55)

1.70 (1.23 to 2.50)

0.16

Intracranial pressure (mmHg)

20 (12 to 30)

15 (14 to 20)

0.27

International normalized ratio

1.22 (1.01 to 1.67)

1.03 (0.92 to 1.15)

0.15

Injury Severity Score

25 (25 to 27)

25 (25 to 32)

0.24

Hemoglobin (g/dl)

11.1 (9.4 to 12.3)

11.4 (10.4 to 13.0)

0.87

Glycemia (g/dl)

161 (142 to 189)

139 (120 to 163)

0.08

Fibrinogen (mg/dl)

376 (246 to 560)

350 (282 to 444)

0.32

Creatinine (mg/dl)

0.95 (0.70 to 1.10)

0.80 (0.70 to 0.90)

0.44

Cerebral perfusion pressure (mmHg)

60 (54 to 69)

68 (57 to 70)

0.46

Bilirubin (mg/dl)

0.75 (0.53 to 1.05)

0.50 (0.40 to 0.87)

0.045

aPTT (seconds)

26 (25 to 31)

28 (25 to 32)

0.86

  1. aAPACHE II, Acute Physiology and Chronic Health Evaluation II; aPTT, Activated partial thromboplastin time; CT, Computed tomography; PaO2, Partial pressure of arterial oxygen; PaO2/FiO2 ratio, Ratio of partial pressure of arterial oxygen to fraction of inspired oxygen. Data shown are number (percentage) or median (25th to 75th percentiles).