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Table 3 Interaction of domains of glycemic control with time in targeted blood glucose rangea

From: Time in blood glucose range 70 to 140 mg/dl >80% is strongly associated with increased survival in non-diabetic critically ill adults

  Number Mortality (%) P -value
NON group    
  TIR-hi    
   Min BG ≥70 mg/dl 1,063 6.49 <0.0001
   Min BG <70 mg/dl 212 18.40  
   CV <20% 1,007 6.85 <0.0001
   CV ≥20% 268 15.30  
   Max BG <180 mg/dl 1,041 6.82 <0.0001
   Max BG ≥180 mg/dl 234 15.81  
  TIR-lo    
   Min BG ≥70 mg/dl 1,027 11.39 <0.0001
   Min BG <70 mg/dl 248 33.87  
   CV <20% 585 9.23 <0.0001
   CV ≥20% 690 21.30  
   Max BG <180 mg/dl 474 10.76 0.0002
   Max BG ≥180 mg/dl 801 18.73  
DM group    
  TIR-hi    
   Min BG ≥70 mg/dl 231 10.82 0.0007
   Min BG <70 mg/dl 142 24.65  
   CV <20% 102 10.78 0.1206
   CV ≥20% 271 18.08  
   Max BG <180 mg/dl 94 14.89 0.8392
   Max BG ≥180 mg/dl 279 16.49  
  TIR-lo    
   Min BG ≥70 mg/dl 281 14.23 0.9802
   Min BG <70 mg/dl 93 15.05  
   CV <20% 61 14.75 0.9014
   CV ≥20% 313 14.38  
   Max BG <180 mg/dl 28 14.29 0.7977
   Max BG ≥180 mg/dl 346 14.45  
  1. aBG, Blood glucose; CV, Coefficient of variation; DM, Diabetes mellitus group; Max, Maximum; Min, Minimum; NON, Non-diabetic group; TIR, Time in targeted blood glucose range 70 to 140 mg/dl; TIR-hi, Time in targeted blood glucose range above median value for non-diabetic and diabetes mellitus groups; TIR-lo, Time in targeted blood glucose range below median value for non-diabetic and diabetes mellitus groups.