Table 3 Interaction of domains of glycemic control with time in targeted blood glucose range^a

From: Time in blood glucose range 70 to 140 mg/dl >80% is strongly associated with increased survival in non-diabetic critically ill adults

			Number	Mortality (%)	P -value
NON group
	TIR-hi
		Min BG ≥70 mg/dl	1,063	6.49	<0.0001
		Min BG <70 mg/dl	212	18.40
		CV <20%	1,007	6.85	<0.0001
		CV ≥20%	268	15.30
		Max BG <180 mg/dl	1,041	6.82	<0.0001
		Max BG ≥180 mg/dl	234	15.81
	TIR-lo
		Min BG ≥70 mg/dl	1,027	11.39	<0.0001
		Min BG <70 mg/dl	248	33.87
		CV <20%	585	9.23	<0.0001
		CV ≥20%	690	21.30
		Max BG <180 mg/dl	474	10.76	0.0002
		Max BG ≥180 mg/dl	801	18.73
DM group
	TIR-hi
		Min BG ≥70 mg/dl	231	10.82	0.0007
		Min BG <70 mg/dl	142	24.65
		CV <20%	102	10.78	0.1206
		CV ≥20%	271	18.08
		Max BG <180 mg/dl	94	14.89	0.8392
		Max BG ≥180 mg/dl	279	16.49
	TIR-lo
		Min BG ≥70 mg/dl	281	14.23	0.9802
		Min BG <70 mg/dl	93	15.05
		CV <20%	61	14.75	0.9014
		CV ≥20%	313	14.38
		Max BG <180 mg/dl	28	14.29	0.7977
		Max BG ≥180 mg/dl	346	14.45

^aBG, Blood glucose; CV, Coefficient of variation; DM, Diabetes mellitus group; Max, Maximum; Min, Minimum; NON, Non-diabetic group; TIR, Time in targeted blood glucose range 70 to 140 mg/dl; TIR-hi, Time in targeted blood glucose range above median value for non-diabetic and diabetes mellitus groups; TIR-lo, Time in targeted blood glucose range below median value for non-diabetic and diabetes mellitus groups.

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