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Table 2 Echocardiographic findings according to the presence or absence of ACP and/or patent foramen ovale PFOa

From: Acute respiratory distress syndrome (ARDS)-associated acute cor pulmonale and patent foramen ovale: a multicenter noninvasive hemodynamic study

Parameters PFO and ACP PFO only ACP only No PFO and no ACP P value
  (n = 8) (n = 21) (n = 36) (n = 130)  
RVEDA/LVEDA (cm2) 0.88 [0.69; 1.34] 0.71 [0.57; 0.77] 0.75 [0.64; 0.92] 0.62 [0.52; 0.72] 0.0002
LV eccentricity index at end-systole 1.32 [1.3; 1.44] 1.07 [1.02; 1.09] 1.33 [1.27; 1.51] 1.06 [1; 1.11] <0.0001
LV eccentricity index at end-diastole 1.13 [1.07; 1.2] 1.08 [1.01; 1.14] 1.09 [1.04; 1.18] 1.07 [1.01; 1.13] 0.21
Cardiac index (L/min/m2) 3.58 [2.78; 3.71] 3.28 [2.84; 4.18] 2.93 [2.62; 3.37] 3.16 [2.6; 3.98] 0.27
LV stroke volume (mL) 59 [46; 68] 61 [48; 76] 58 [49; 61] 63 [52; 73] 0.09
LVEDV (mL) 67 [51; 85] 85 [54; 100] 79 [66; 93] 87 [68; 106] 0.04
LVEF (%) 65 [55; 74] 62 [46; 70] 58 [48; 66] 56 [44; 68] 0.60
RVFAC (%) 18 [15; 25] 32 [24; 40] 26 [17; 34] 34 [26; 42] 0.0007
TAPSE (mm) 15 [14; 20] 20 [17; 23] 18 [16; 20] 20 [16; 23] 0.02
Doppler-derived sPAP (mmHg) 46 [41; 60] 50 [39; 67] 45 [37; 55] 42 [35; 49] 0.17
  1. aResults are expressed as median values with 25th to 75th percentiles. ACP, acute cor pulmonale; PFO, patent foramen ovale; RVEDA, right ventricular end-diastolic area; LVEDA, left ventricular end-diastolic area; LV, left ventricle; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; RVFAC, right ventricular fractional area change; TAPSE, tricuspid annular plane systolic elevation; sPAP, systolic pulmonary artery pressure.