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Table 3 Comparison of biochemical parameters on days with and without renal tubular acidosis

From: Renal tubular acidosis is highly prevalent in critically ill patients

 

No RTA (318 days)

RTA (55 days)

P value

Arterial pH

7.41 ± 0.07

7.40 ± 0.19

0.421

pCO2

45.3 ± 13.1

39.2 ± 4.9

<0.001

Standard bicarbonate (mmol/L)

27 ± 5

24 ± 2

<0.001

Standard base excess (mmol/L)

3.4 ± 5.1

−0.48 ± 3.51

<0.001

  BESodium (mmol/L)

0.0 ± 1.4

0.2 ± 1.2

0.317

  BEChloride (mmol/L)

−1.4 ± 4.1

−6.9 ± 1.5

<0.001

  BEAlbumin (mmol/L)

4.2 ± 1.2

4.2 ± 1.0

0.969

  BEUMA (mmol/L)

0.7 ± 2.9

2.3 ± 2.0

<0.001

Serum sodium (mmol/L)

140 ± 5

141 ± 4

0.317

Serum potassium (mmol/L)

4.1 ± 0.5

4.1 ± 0.4

0.894

Serum chloride (mmol/L)

106 ± 5

112 ± 3

<0.001

Serum phosphate (mmol/L)

0.97 ± 0.36

0.89 ± 0.28

0.121

Serum lactate (mmol/L)

1.4 ± 0.9

1.2 ± 0.6

0.319

Urine chloride (mmol/L)

80 ± 42

83 ± 45

0.163

Creatinine clearance (mL/min)

63 (26-106)

83 (46-125)

0.786

NaCl 0.9% infusion per day (mL)

250 (10-550)

300 (114-857)

0.268

  1. Data are means ± standard deviation (SD), median (25th to 75th percentile) or absolute counts. RTA, renal tubular acidosis; BESodium, base excess attributable to changes of free water; BEChloride, base excess attributable to changes of plasma chloride; BEAlbumin, base excess attributable to changes of plasma albumin; BEUMA, base excess attributable to unmeasured anions.