Table 1 Admission reason and patients’ characteristics

  Respiratory failure

31

  St.p. Cardiopulmonary resuscitation

21

  Sepsis/septic shock

8

  Cardiogenic/hypovolemic shock

4

  Coma

5

  Esophageal/GI bleeding

6

  Acute liver failure

1

  Intoxication

1

  Necrotizing pancreatitis

1

  Postoperative

21

Diabetes mellitus

25

Arterial hypertension

41

Chronic renal failure

18

Liver cirrhosis

11

Congestive heart failure

45

Acute or acute-on-chronic renal failure

13

Nephrotoxic medication during study period

93

Amphotericin B

4

Neuroleptic drugs

13

Combined antibiotic schemes

37

Plasmapheresis

3

Sedoanalgesia

55

Muscle relaxants

3

Calcineurin inhibitors

5

Shock during study period

57

Sepsis during study period

42

Mechanical ventilation during study period

73

Age (years)

62 ± 16

Gender (female/male)

40/60

BMI (kg/m²)

26 ± 5

SOFA score

8 ± 4

APACHE II score

20 ± 8

SAPS II score

51 ± 20

Length of ICU stay (days)

6 (3 - 11)

ICU mortality (non-survivors)

14

Serum creatinine^* (mg/dL)

1.42 ± 0.88

Blood urea nitrogen^* (mg/dL)

30 ± 22

Serum uric acid^* (mg/dL)

5.2 ± 2.5

Serum phosphate^* (mg/dL)

1.12 ± 0.37

Arterial pH^*

7.37 ± 0.09

Standard bicarbonate^* (mmol/L)

24.8 ± 4.7

Serum anion gap^* (mmol/L)

11 ± 3.7

Urine anion gap^* (mmol/L)

43 ± 42

Creatinine clearance^# (mL/min)

66 (33 - 108)

Urine volume^# (in 24 h)

1550 (920 - 2720)