Pooled analysis of determinants of changes in ICU length of stay (days) in implementation studies (n = 7) that included delirium-oriented interventions. Determinants of ICU length of stay reduction that were studied were: use of either the guideline for the management of pain, agitation and delirium (PAD) or the awakening and breathing coordination, choice of sedative, delirium monitoring and management and early mobility (ABCDE) bundle (a) or use of high or low number of implementation strategies (b). (c) Impact of high or low number of strategies within the studies reporting ICU length of stay and using PAD/ABCDE (n = 4). See text for more details. Study by Radtke reported multiple populations and these were separately assessed.