Figure 4
From: Hemopexin in severe inflammation and infection: mouse models and human diseases
Correlation of IL-6 concentrations with bacteremia or mouse hemopexin concentrations. C57BL/6 mice (n = 48) were subjected to intraperitoneal implantation of E. coli O4 104 to 107 cfu/mouse. Cardiac puncture was performed 24 hours after the laparotomy to collect blood for interleukin 6 (IL-6) and hemopexin measurements. Blood samples were also diluted and spread on Luria Broth agar plates and the colonies were counted after overnight incubation at 37°C. Bacteremia was calculated and presented as cfu/ml. Pearson correlation analysis was performed. (A) Log IL-6 (pg/ml) vs. Log E. coli (cfu/ml) (6 out of 48 mice without bacteremia were not included); (B) Log IL-6 (pg/ml) vs. mouse hemopexin (mHx) (μg/ml). Data were from nine independent experiments.