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Figure 3 | Critical Care

Figure 3

From: Hemopexin in severe inflammation and infection: mouse models and human diseases

Figure 3

Plasma hemopexin concentrations in mouse peritonitis model with fibrin clot. C57BL/6 mice were subjected to intraperitoneal implantation of fibrin clots only (sham, n = 6) or with blood clots (Bld, n = 9) or with E. coli O4 104 cfu/mouse (n = 5) or 106 cfu/mouse (n = 37, 8 mice died) or E. coli O4 106 cfu/mouse with ceftriaxone (ceftr.) (1 mg/mouse) (n = 12) injected intramuscularly 2 hours after the laparotomy. Mouse hemopexin (mHx) concentrations were measured in naïve mice (n = 12) or in treated mice 24 hours after the laparotomy. Data are analyzed by one-way analysis of variance (ANOVA) and Tukey’s test was done for pairwise comparisons. Horizontal lines represent means. Data were from nine independent experiments. ** P <0.01; *** P <0.001; **** P <0.0001.

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