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Table 2 Plasma concentration of inflammatory analytes used to make the control and severe sepsis cytokine mixtures

From: Human severe sepsis cytokine mixture increases β2-integrin-dependent polymorphonuclear leukocyte adhesion to cerebral microvascular endothelial cells in vitro

Analyte Control Severe sepsis Fold increase P value
MCP-1 41.8 ± 12.1 1067.8 ± 196.4 25 <0.001
G-CSF 29.3 ± 9.5 938.4 ± 278.5 32 <0.001
IL-8 10.0 ± 0.0 211.9 ± 43.4 21 <0.001
HGF 290.3 ± 60.8 3346.8 ± 570.5 12 <0.001
MIP-1β 49.7 ± 12.1 381.1 ± 116.0 8 <0.001
IP-10 214.4 ± 26.8 1552.0 ± 254.5 7 <0.001
GROα 92.5 ± 24.2 637.5 ± 136.3 7 <0.001
IL-6 80.8 ± 31.8 387.6 ± 158.4 5 0.017
  1. Plasma was obtained from severe sepsis patients and compared to plasma from age- and sex-matched healthy controls. Analytes were measured with antibody microarray and presented as mean ± SE. Values are in ng/mL (n = 20 per group). MCP-1-monocyte chemotactic protein-1; GCSF-granulocyte colony-stimulating factor; IL-8- interleukin-8; HGF- hepatocyte growth factor; MIP-1β- macrophage inflammatory protein-1 beta; IP-10- interferon-inducible protein 10 kDa; GRO-α- growth-regulated oncogene alpha; IL-6- interleukin-6.