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Figure 5 | Critical Care

Figure 5

From: Tryptase is involved in the development of early ventilator-induced pulmonary fibrosis in sepsis-induced lung injury

Figure 5

Immunohistochemical localization of tryptase and PAR-2. Brown color staining indicates positive staining and blue/violet indicates nuclei counterstained with hematoxylin. Tryptase and PAR-2 staining increased markedly in high-VT lungs. C: non-septic, anesthetized, non-ventilated, spontaneous breathing; S: septic, anesthetized, non-ventilated, spontaneous breathing; SLVT + PEEP: septic, ventilated with low tidal volume plus positive end-expiratory pressure (PEEP) of 10 cmH2O; SHVT: septic, ventilated with high tidal volume. ×400 magnification. PAR-2, protease-activated receptor-2; VT, tidal volume.

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Critical Care

ISSN: 1364-8535