Figure 4

Western blot analysis of PAR-2. The upper panel is a representative gel for each experimental group. The lower panel represents the relative optical density of tryptase normalized against β-actin. C: non-septic, anesthetized, non-ventilated, spontaneous breathing; S: septic, anesthetized, non-ventilated, spontaneous breathing; SLVT + PEEP: septic, ventilated with low tidal volume plus positive end-expiratory pressure (PEEP) of 10 cmH₂O; SHVT: septic, ventilated with high tidal volume. Six animals were quantified in each group. ^¶ P <0.001 vs. S.