Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: a quasi-experimental study in surgical intensive care unit

Table 2 Healthcare-associated MRSA infection rates

Variable	Period 1 Non-intervention (n = 327)	Period 2 Intervention (n = 314)	Period 3 Non-intervention (n = 899)	Period 4 Intervention (n = 833)
Total patient days (SICU)	2,792	2,371	5,875	5,434
Total patient days (in-hospital)	7,028	6,817	17,387	16,523
% of patients screened at ICU admission	-	67.8% (213/314)	-	64.5% (538/833)
MRSA positive rate of surveillance culture	-	11.3% (24/213)	-	6.1% (33/538)
MRSA infection rate (‰) (SICU)	3.58	0.42	2.21	0.18
SICU MRSA infection (number)	10	1^a	13	1^a
BSI infection	6	0	5	0
RTI infection	3	1	5	1
UTI infection	0	0	2	0
SSI infection	0	0	0	0
Other infection sites (CVSI, EENTI)	1	0	1	0
MRSA infection rate (‰) (in-hospital)	1.42	0.29	0.75	0.24
In-hospital MRSA infection (number)	10	2^b	13	4^b

^aBoth cases had negative surveillance culture at the time of SICU admission. ^bIncluding the two SICU MRSA infection cases. Of the four MRSA infection cases that occurred after transfer to general wards, three cases had negative surveillance culture at the time of SICU admission, and the other had positive surveillance culture at the time of SICU admission. BSI: Bloodstream infection; CVSI: Cardiovascular system infection; EENTI: eye, ear, nose, throat, or mouth infection; MRSA: Methicillin-resistant Staphylococcus aureus; RTI: Respiratory tract infection; SICU: Surgical intensive care unit; SSI: Surgical site infection; UTI: Urinary tract infection.

ISSN: 1364-8535