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Table 5 Clinical and ventilation characteristics at the time of ECMO initiation according to survival status

From: External validation of scores proposed for estimation of survival probability of patients with severe adult respiratory distress syndrome undergoing extracorporeal membrane oxygenation therapy: a retrospective study

Characteristic All patients (n = 51) Status 6 months post-ICU Pvalue
  Alive (n = 28) Dead (n = 23)  
Ventilation parameters     
  PaO2/FiO2 57 (49-74) 55 (44-67) 64 (52-82) 0.049
  FiO2 100 (100-100) 100 (100-100) 100 (100-100) 0.99
  PEEP (cmH2O) 12 (10-15) 13 (10-15) 12 (10-15) 0.73
  Tidal volume (ml/PBW kg) 8 (5-8) 7 (5-8) 8 (5-9) 0.51
  Respiratory rate (per minute) 28 (24-33) 30 (24-36) 26 (23-31) 0.20
  Peak inspiratory pressure (cmH2O) 34 (31-37) 33 (31-37) 34 (29-37) 0.70
Pre-ECMO blood gases     
  pH 7.27 (7.12-7.35) 7.24 (7.11-7.31) 7.29 (7.15-7.37) 0.33
  PaO2 (mmHg) 57 (49-73) 55 (44-67) 63 (52-74) 0.20
  PaCO2 (mmHg) 57 (47-76) 57 (48-76) 58 (47-76) 0.85
  HCO3 (mmol/l) 24 (18-29) 24 (19-29) 23 (18-29) 0.88
  SaO2 (%) 86.6 (78.0-92.7) 87 (76-93) 86 (82-92) 0.80
  Lactate arterial (mmol/l) 1.6 (0.7-2.9) 1.6 (0.9-2.8) 1.6 (0.7-3.0) 0.75
Rescue therapy     
  Prone positioning 9 (18) 3 (11) 6 (26) 0.27
  Nitric oxide 26 (51) 15 (54) 11 (48) 0.78
Bilateral infiltration 48 (94) 27 (96) 21 (91) 0.58
Pre-ECMO steroids 23 (45) 11 (39) 12 (52) 0.41
Pre-ECMO vasopressors 46 (90) 25 (89) 21 (91) 0.81
Pre-ECMO pneumothorax 6 (12) 2 (7) 4 (17) 0.39
Mobile ECMO team 6 (12) 3 (11) 3 (13) 0.80
Interval (days)     
  Hospital to ICU admission 1 (0-3) 1 (0-3) 1 (0-4) 0.89
  Hospital to ECMO center admission 4 (1-8) 2 (1-6) 7 (4-10) 0.046
  Hospital admission to ECMO 7 (4-13) 4 (2-13) 9 (6-14) 0.03
  ICU admission to ECMO 4 (1-8) 3 (1-6) 7 (3-10) 0.03
  MV to ECMO 2 (1-8) 1 (1-6) 4 (1-10) 0.14
  1. Values are expressed as median (interquartile range) or n (%). ECMO, extracorporeal membrane oxygenation; FiO2, fraction of inspired oxygen; HCO3, bicarbonate; MV, mechanical ventilation; PaO2, partial pressure of oxygen; PaCO2, partial pressure of carbon dioxide; PBW, predicted body weight; PEEP, positive end-expiratory pressure; SaO2, oxygen saturation.