Skip to main content

Table 5 Clinical and ventilation characteristics at the time of ECMO initiation according to survival status

From: External validation of scores proposed for estimation of survival probability of patients with severe adult respiratory distress syndrome undergoing extracorporeal membrane oxygenation therapy: a retrospective study

Characteristic

All patients (n = 51)

Status 6 months post-ICU

Pvalue

 

Alive (n = 28)

Dead (n = 23)

 

Ventilation parameters

    

  PaO2/FiO2

57 (49-74)

55 (44-67)

64 (52-82)

0.049

  FiO2

100 (100-100)

100 (100-100)

100 (100-100)

0.99

  PEEP (cmH2O)

12 (10-15)

13 (10-15)

12 (10-15)

0.73

  Tidal volume (ml/PBW kg)

8 (5-8)

7 (5-8)

8 (5-9)

0.51

  Respiratory rate (per minute)

28 (24-33)

30 (24-36)

26 (23-31)

0.20

  Peak inspiratory pressure (cmH2O)

34 (31-37)

33 (31-37)

34 (29-37)

0.70

Pre-ECMO blood gases

    

  pH

7.27 (7.12-7.35)

7.24 (7.11-7.31)

7.29 (7.15-7.37)

0.33

  PaO2 (mmHg)

57 (49-73)

55 (44-67)

63 (52-74)

0.20

  PaCO2 (mmHg)

57 (47-76)

57 (48-76)

58 (47-76)

0.85

  HCO3 (mmol/l)

24 (18-29)

24 (19-29)

23 (18-29)

0.88

  SaO2 (%)

86.6 (78.0-92.7)

87 (76-93)

86 (82-92)

0.80

  Lactate arterial (mmol/l)

1.6 (0.7-2.9)

1.6 (0.9-2.8)

1.6 (0.7-3.0)

0.75

Rescue therapy

    

  Prone positioning

9 (18)

3 (11)

6 (26)

0.27

  Nitric oxide

26 (51)

15 (54)

11 (48)

0.78

Bilateral infiltration

48 (94)

27 (96)

21 (91)

0.58

Pre-ECMO steroids

23 (45)

11 (39)

12 (52)

0.41

Pre-ECMO vasopressors

46 (90)

25 (89)

21 (91)

0.81

Pre-ECMO pneumothorax

6 (12)

2 (7)

4 (17)

0.39

Mobile ECMO team

6 (12)

3 (11)

3 (13)

0.80

Interval (days)

    

  Hospital to ICU admission

1 (0-3)

1 (0-3)

1 (0-4)

0.89

  Hospital to ECMO center admission

4 (1-8)

2 (1-6)

7 (4-10)

0.046

  Hospital admission to ECMO

7 (4-13)

4 (2-13)

9 (6-14)

0.03

  ICU admission to ECMO

4 (1-8)

3 (1-6)

7 (3-10)

0.03

  MV to ECMO

2 (1-8)

1 (1-6)

4 (1-10)

0.14

  1. Values are expressed as median (interquartile range) or n (%). ECMO, extracorporeal membrane oxygenation; FiO2, fraction of inspired oxygen; HCO3, bicarbonate; MV, mechanical ventilation; PaO2, partial pressure of oxygen; PaCO2, partial pressure of carbon dioxide; PBW, predicted body weight; PEEP, positive end-expiratory pressure; SaO2, oxygen saturation.