Characteristic | All patients (n = 51) | Status 6 months post-ICU | Pvalue | |
---|---|---|---|---|
Alive (n = 28) | Dead (n = 23) | |||
Ventilation parameters | ||||
PaO2/FiO2 | 57 (49-74) | 55 (44-67) | 64 (52-82) | 0.049 |
FiO2 | 100 (100-100) | 100 (100-100) | 100 (100-100) | 0.99 |
PEEP (cmH2O) | 12 (10-15) | 13 (10-15) | 12 (10-15) | 0.73 |
Tidal volume (ml/PBW kg) | 8 (5-8) | 7 (5-8) | 8 (5-9) | 0.51 |
Respiratory rate (per minute) | 28 (24-33) | 30 (24-36) | 26 (23-31) | 0.20 |
Peak inspiratory pressure (cmH2O) | 34 (31-37) | 33 (31-37) | 34 (29-37) | 0.70 |
Pre-ECMO blood gases | ||||
pH | 7.27 (7.12-7.35) | 7.24 (7.11-7.31) | 7.29 (7.15-7.37) | 0.33 |
PaO2 (mmHg) | 57 (49-73) | 55 (44-67) | 63 (52-74) | 0.20 |
PaCO2 (mmHg) | 57 (47-76) | 57 (48-76) | 58 (47-76) | 0.85 |
HCO3− (mmol/l) | 24 (18-29) | 24 (19-29) | 23 (18-29) | 0.88 |
SaO2 (%) | 86.6 (78.0-92.7) | 87 (76-93) | 86 (82-92) | 0.80 |
Lactate arterial (mmol/l) | 1.6 (0.7-2.9) | 1.6 (0.9-2.8) | 1.6 (0.7-3.0) | 0.75 |
Rescue therapy | ||||
Prone positioning | 9 (18) | 3 (11) | 6 (26) | 0.27 |
Nitric oxide | 26 (51) | 15 (54) | 11 (48) | 0.78 |
Bilateral infiltration | 48 (94) | 27 (96) | 21 (91) | 0.58 |
Pre-ECMO steroids | 23 (45) | 11 (39) | 12 (52) | 0.41 |
Pre-ECMO vasopressors | 46 (90) | 25 (89) | 21 (91) | 0.81 |
Pre-ECMO pneumothorax | 6 (12) | 2 (7) | 4 (17) | 0.39 |
Mobile ECMO team | 6 (12) | 3 (11) | 3 (13) | 0.80 |
Interval (days) | ||||
Hospital to ICU admission | 1 (0-3) | 1 (0-3) | 1 (0-4) | 0.89 |
Hospital to ECMO center admission | 4 (1-8) | 2 (1-6) | 7 (4-10) | 0.046 |
Hospital admission to ECMO | 7 (4-13) | 4 (2-13) | 9 (6-14) | 0.03 |
ICU admission to ECMO | 4 (1-8) | 3 (1-6) | 7 (3-10) | 0.03 |
MV to ECMO | 2 (1-8) | 1 (1-6) | 4 (1-10) | 0.14 |