External validation of scores proposed for estimation of survival probability of patients with severe adult respiratory distress syndrome undergoing extracorporeal membrane oxygenation therapy: a retrospective study

Table 2 RESP score parameters [10]

Parameter	Score
Age (years)
18-49	0
50-59	−2
≥60	−3
Immunocompromised status^a	−2
Mechanical ventilation prior to initiation of ECMO
<48 hours	3
48 hours to 7 days	1
>7 days	0
Acute respiratory diagnosis group (select only one)
Viral pneumonia	3
Bacterial pneumonia	3
Asthma	11
Trauma and burn	3
Aspiration pneumonitis	5
Other acute respiratory diagnoses	1
Nonrespiratory and chronic respiratory diagnoses	0
Central nervous system dysfunction^b	−7
Acute associated (nonpulmonary) infection^c	−3
Neuromuscular blockade agents before ECMO	1
Nitric oxide use before ECMO	−1
Bicarbonate infusion before ECMO	−2
Cardiac arrest before ECMO	−2
PaCO₂ (mmHg)
<75	0
≥75	−1
Peak inspiratory pressure (cmH₂O)
<42	0
≥42	−1
Total score	−22 to 15

^aImmunocompromised is defined as hematological malignancies, solid tumor, solid organ transplantation, human immunodeficiency virus, and/or cirrhosis. ^bCentral nervous system dysfunction diagnosis combined neurotrauma, stroke, encephalopathy, cerebral embolism, and seizure and epileptic syndrome. ^cAcute associated (nonpulmonary) infection is defined as another bacterial, viral, parasitic, or fungal infection that did not involve the lung. An online calculator is available at [18]. ECMO, extracorporeal membrane oxygenation; PaCO₂, partial pressure of carbon dioxide; RESP, Respiratory ECMO Survival Prediction.

ISSN: 1364-8535