Table 3 Univariate and multivariate analysis of factors associated with mortality in 261 injured patients undergoing pre-hospital rapid sequence induction of anaesthesia by a helicopter emergency medicine service
Factor | Survived (n = 193) | Died (n = 46) | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|---|---|
Crude odds ratio (95% CI) | P -value | Adjusted odds ratio (95% CI) | P -value | |||
Age, years | 39 (23 to 55) | 51 (40 to 63) | 1.029 (1.012, 1.047) | 0.001 | 1.032 (1.006, 1.059) | 0.016 |
Gender | ||||||
Male | 140 (80.9) | 33 (19.1) | 1.041 (0.509, 2.128) | 0.913 | ||
Female | 53 (80.3) | 13 (19.7) | ||||
Mechanism of injury | ||||||
Blunt | 183 (79.9) | 46 (20.1) | - | 0.216 | ||
Penetrating | 10 (100.0) | 0 | ||||
Initial physiology | ||||||
Glasgow coma scale | 10 (7 to 13) | 4 (3 to 10) | 0.759 (0.724, 0.874) | <0.0001 | 0.780 (0.680, 0.896) | <0.0001 |
Heart rate | 90 (76 to 107) | 95 (68 to 125) | 1.006 (0.993, 1.018) | 0.363 | ||
Systolic blood pressure | 127 (112 to 144) | 120 (101 to 144) | 0.994 (0.981, 1.007) | 0.361 | ||
Injury severity score | 21 (13 to 34) | 34 (27 to 43) | 1.077 (1.041, 1.114) | <0.0001 | 1.054 (1.013, 1.098) | 0.009 |
Rapid sequence induction dose | ||||||
Full | 148 (86.6) | 23 (13.4) | 3.289 (1.687, 6.410) | <0.0001 | 1.901 (0.685, 5.272) | 0.217 |
Reduced | 45 (66.2) | 23 (33.8) | ||||
Rapid sequence induction protocol | ||||||
ES | 85 (81.0) | 20 (19.0) | 1.023 (0.535, 1.869) | 1.000 | ||
FKR | 108 (80.6) | 26 (19.4) | ||||
Haemodynamic response* | ||||||
Normal | 79 (88.8) | 10 (11.2) | 1.541 (0.660, 3.601) | 0.317 | ||
Abnormal | 82 (83.7) | 16 (16.3) | ||||