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Table 2 Hemodynamic variables

From: A high mean arterial pressure target is associated with improved microcirculation in septic shock patients with previous hypertension: a prospective open label study

  MAP = 65 mmHg Usual MAP P
Norepinephrine dose (μg/kg/minute) 0.08 (0.04-0.34) 0.25 (0.16-0.68)* <0.001
Systolic arterial pressure (mmHg) 107 ± 19 140 ± 15* <0.001
Diastolic arterial pressure (mmHg) 53 ± 7 66 ± 9* <0.001
Mean arterial pressure (mmHg) 71 ± 8 91 ± 7* <0.001
Heart rate (beats/minute) 100 ± 24 99 ± 21 0.793
Central venous pressure (mmHg) 11 ± 4 13 ± 4* 0.002
Cardiac output (l/minute) 5.4 ± 1.4 6.4 ± 2.1* 0.001
Stroke volume (ml) 57.5 ± 21.2 67.0 ± 26.7* 0.003
Urine output (ml/hour) 56 ± 6 55 ± 6 0.921
Hemoglobin (g/dl) 9.4 ± 1.9 9.5 ± 2.0 0.605
Arterial pH 7.38 ± 0.06 7.39 ± 0.06 0.305
Lactate (mmol/l) 2.3 ± 2.3 2.2 ± 2.3 0.598
Arterial partial pressure of oxygen (mmHg) 132 ± 37 142 ± 51 0.250
Arterial partial pressure of carbon dioxide (mmHg) 30 ± 6 29 ± 6 0.303
Arterial hemoglobin saturation (%) 97.4 ± 1.8 98.0 ± 1.6 0.129
PaO2:FiO2 ratio (mmHg) 259 ± 99 291 ± 104* 0.003
Central venous hemoglobin saturation (%) 81 ± 7 83 ± 7* 0.001
  1. *P < 0.05 versus baseline of mean arterial pressure 65 mmHg. MAP, mean arterial pressure; PaO2:FiO2, arterial oxygen partial pressure to fractional inspired oxygen. Data presented as means ± SD or median (interquartile range).