|
Norepinephrine dose (μg/kg/minute)
|
0.08 (0.04-0.34)
|
0.25 (0.16-0.68)*
|
<0.001
|
|
Systolic arterial pressure (mmHg)
|
107 ± 19
|
140 ± 15*
|
<0.001
|
|
Diastolic arterial pressure (mmHg)
|
53 ± 7
|
66 ± 9*
|
<0.001
|
|
Mean arterial pressure (mmHg)
|
71 ± 8
|
91 ± 7*
|
<0.001
|
|
Heart rate (beats/minute)
|
100 ± 24
|
99 ± 21
|
0.793
|
|
Central venous pressure (mmHg)
|
11 ± 4
|
13 ± 4*
|
0.002
|
|
Cardiac output (l/minute)
|
5.4 ± 1.4
|
6.4 ± 2.1*
|
0.001
|
|
Stroke volume (ml)
|
57.5 ± 21.2
|
67.0 ± 26.7*
|
0.003
|
|
Urine output (ml/hour)
|
56 ± 6
|
55 ± 6
|
0.921
|
|
Hemoglobin (g/dl)
|
9.4 ± 1.9
|
9.5 ± 2.0
|
0.605
|
|
Arterial pH
|
7.38 ± 0.06
|
7.39 ± 0.06
|
0.305
|
|
Lactate (mmol/l)
|
2.3 ± 2.3
|
2.2 ± 2.3
|
0.598
|
|
Arterial partial pressure of oxygen (mmHg)
|
132 ± 37
|
142 ± 51
|
0.250
|
|
Arterial partial pressure of carbon dioxide (mmHg)
|
30 ± 6
|
29 ± 6
|
0.303
|
|
Arterial hemoglobin saturation (%)
|
97.4 ± 1.8
|
98.0 ± 1.6
|
0.129
|
|
PaO2:FiO2 ratio (mmHg)
|
259 ± 99
|
291 ± 104*
|
0.003
|
|
Central venous hemoglobin saturation (%)
|
81 ± 7
|
83 ± 7*
|
0.001
|
