Doubling survival and improving clinical outcomes using a left ventricular assist device instead of chest compressions for resuscitation after prolonged cardiac arrest: a large animal study

Table 2 Hemodynamics and blood gas data in crossover experiments^a

	BL, n =10	PR 10, n =6	PR 30, n =6	PR 60, n =6	PR 120, n =6
HR (bpm)	101 ± 15	158 ± 44	148 ± 40	124 ± 39	134 ± 31
MAP (mmHg)	113 ± 9	86 ± 21	65 ± 14	69 ± 18	75 ± 21
CO (L/min)	5.4 ± 1.2	5.6 ± 1.1	4.2 ± 2.5	2.3 ± 0.6	2.8 ± 1.2
MPAP (mmHg)	20 ± 5	21 ± 6	17 ± 4	19 ± 5	21 ± 4
PaO₂ (mmHg)	104.3 ± 9.5	492.8 ± 54.3	487.0 ± 39.7	109.8 ± 17.6	112.1 ± 12.0
PaCO₂ (mmHg)	41.5 ± 3.6	45.5 ± 7.2	38.0 ± 3.9	38.3 ± 5.2	34.3 ± 3.1
Lactate (mmol/L)	1.2 ± 1.1	7.8 ± 1.4	7.8 ± 1.7	7.2 ± 2.0	5.7 ± 2.8
Glucose (mmol/L)	105 ± 6	209 ± 85	201 ± 59	197 ± 47	186 ± 44
pH	7.46 ± 0.04	7.22 ± 0.09	7.31 ± 0.05	7.37 ± 0.07	7.40 ± 0.05

^aHemodynamic and blood gas data in ten pigs treated with intravascular cardiopulmonary resuscitation after failure of standard cardiopulmonary resuscitation at baseline (BL) or at 10 (PR 10), 30 (PR 30), 60 (PR 60) or 120 (PR 120) minutes following return of spontaneous circulation. All animals received a bolus dose of 30 μg/kg epinephrine intravenously twice during cardiopulmonary resuscitation. HR, Heart rate; MAP, Mean arterial pressure; CO, Cardiac output; MPAP, Mean pulmonary artery pressure; PaO₂, Arterial oxygen tension; PaCO₂, Arterial carbon dioxide tension. Data are presented as the mean ± standard deviation.

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