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Table 3 Urinary melatonin and cortisol levels in the groups during the night before surgery, and the first and second nights after surgery

From: Effects of earplugs and eye masks combined with relaxing music on sleep, melatonin and cortisol levels in ICU patients: a randomized controlled trial

Variables Intervention group Control group
  Pre-surgery night First night post surgery Second night post surgery P -value Pre-surgery night First night post surgery Second night post surgery P -value
6-SMT, ug 23.3 ± 24.3a 6.1 ± 9.9a 8.3 ± 12.6a 0.01 33.9 ± 99.9a 5.6 ± 12.7a 7.1 ± 9.8a 0.00
Cortisol, ug 10.3 ± 8.3b 95.9 ± 71.2b 82.5 ± 47.3b 0.00 13.8 ± 8.8b 82.9 ± 56.9b 74.9 ± 56.3b 0.00
  1. aNo significant differences were found between the two groups in 6-SMT levels during the night before surgery (P = 0.22), or the first (P = 0.61) and second postoperative nights (P = 0.97). bNo significant differences were found in cortisol levels between the two groups during the night before surgery (P = 0.33), or the first (P = 0.53) and second postoperative nights (P = 0.65).