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Table 1 Demographic data, co-morbidities and critical care data for non muscle-wasting (n = 19) and muscle-wasting patients (n = 23)

From: MiR-181a: a potential biomarker of acute muscle wasting following elective high-risk cardiothoracic surgery

  Non muscle-wasting patients(n = 19) Muscle-wasting patients (n = 23) P -value ( t -test, Mann-Whitney# , chi-squared*)
Demographic data    
Age, years 65.7 ± 17.2 62.0 ± 16.2 0.47
Sex, male/female 9/10 12/11 0.76*
Body mass index, kg/m2a 26.6 ± 4.6 24.7 ± 4.1 0.18
EuroSCORE 5.3 ± 1.8 5.5 ± 2.6 0.76
Pre-operative creatinine, umol/La 81.3 ± 23.6 77.3 ± 17.1 0.52
Pre-operative creatinine clearance, ml/minutea 84.7 ± 36.1 86.8 ± 34.7 0.66
Pre-operative co-morbidities, n    
Ischaemic heart disease 10 8 0.24*
Structural heart disease 9 11 0.97*
Dysrhythmia 2 3 0.80*
Systemic hypertension 7 5 0.94*
Pulmonary hypertension 1 2 0.66*
Hypercholesterolaemia 7 10 0.66*
Congenital cardiac disease 3 6 0.42*
Diabetes 3 1 0.21*
Obstructive lung disease 3 2 0.45*
Outcome data    
C-reactive protein day 2 165 ± 60 189 ± 68 0.23
ICU length of stay, days, median (IQR) 1 (1 to 2.5) 2 (1 to 3) 0.62#
Hospital length of stay, days, median (IQR) 8 (7 to 11) 9 (8 to 10.5) 0.44#
  1. Data presented as mean ± SD unless otherwise stated. aWeight unavailable for two patients in the muscle-wasting group, therefore, n = 21. Data adapted from previously published study [17]. p values calcultated by t-test, # - Man-Whitney or * - Chi-squared as appropriate.