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Table 3 Multivariable analysis of variables associated with 90-day mortalitya (n =2,312)

From: Severe and multiple hypoglycemic episodes are associated with increased risk of death in ICU patients

Variables

Odds ratio (95% CI)

P -value

Age (per 1 yr)

1.024 (1.017 to 1.031)

<0.001

Body mass index (per 1 kg/m2)

0.979 (0.963 to 0.995)

0.008

SAPS II score (per 1 point)

1.019 (1.012 to 1.025)

<0.001

SOFA score (per 1 point)

1.086 (1.053 to 1.120)

<0.001

McCabe score (per 1 point)

1.587 (1.357 to 1.885)

<0.001

Type of patient

  
 

Medical

1

 

Scheduled surgical

0.663 (0.532 to 0.827)

<0.001

 

Emergency surgical

0.460 (0.321 to 0.657)

<0.001

Moderate hypoglycemia

1.114 (0.865 to 1.436)

0.40

Severe hypoglycemia

1.571 (1.055 to 2.339)

0.03

Number of hypoglycemic events ≥3

1.834 (1.361 to 2.471)

<0.001

Mean blood glucose (per 1 mmol/L)

1.086 (1.010 to 1.168)

0.03

Blood glucose CV <0.20

1

Blood glucose CV 0.20 to 0.39

1.155 (0.906 to 1.472)

0.24

Blood glucose CV ≥0.40

1.041 (0.698 to 1.552)

0.84

Computerized blood glucose control

0.786 (0.639 to 0.958)

0.02

  1. aCV, Coefficient of variation; OR, Odds ratio; CI, Confidence interval; c-index =0.757; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.