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Table 3 Multivariable analysis of variables associated with 90-day mortalitya (n =2,312)

From: Severe and multiple hypoglycemic episodes are associated with increased risk of death in ICU patients

Variables Odds ratio (95% CI) P -value
Age (per 1 yr) 1.024 (1.017 to 1.031) <0.001
Body mass index (per 1 kg/m2) 0.979 (0.963 to 0.995) 0.008
SAPS II score (per 1 point) 1.019 (1.012 to 1.025) <0.001
SOFA score (per 1 point) 1.086 (1.053 to 1.120) <0.001
McCabe score (per 1 point) 1.587 (1.357 to 1.885) <0.001
Type of patient   
  Medical 1
  Scheduled surgical 0.663 (0.532 to 0.827) <0.001
  Emergency surgical 0.460 (0.321 to 0.657) <0.001
Moderate hypoglycemia 1.114 (0.865 to 1.436) 0.40
Severe hypoglycemia 1.571 (1.055 to 2.339) 0.03
Number of hypoglycemic events ≥3 1.834 (1.361 to 2.471) <0.001
Mean blood glucose (per 1 mmol/L) 1.086 (1.010 to 1.168) 0.03
Blood glucose CV <0.20 1
Blood glucose CV 0.20 to 0.39 1.155 (0.906 to 1.472) 0.24
Blood glucose CV ≥0.40 1.041 (0.698 to 1.552) 0.84
Computerized blood glucose control 0.786 (0.639 to 0.958) 0.02
  1. aCV, Coefficient of variation; OR, Odds ratio; CI, Confidence interval; c-index =0.757; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.