Table 2 Blood glucose metrics^a

Initial blood glucose, mmol/L

8.9 (4.0)

9.6 (4.6)^b

9.8 (5.5)^b

9.7 (4.2)^b

Mean morning blood glucose, mmol/L

7.2 (2.3)

6.8 (1.6)^b

6.8 (1.8)^b

6.7 (1.8)^b

Mean blood glucose, mmol/L

7.2 (1.7)

6.7 (1.2)^b

6.8 (1.5)^b

6.6 (1.2)^b

Maximum blood glucose, mmol/L

11.3 (1.4)

12.8 (4.1)^b

14.6 (5.1)^bc

14.2 (4.9)^b

Minimum Blood glucose, mmol/L

4.6 (1.4)

2.9 (0.3)

1.7 (0.4)

2.2 (0.6)

Blood glucose standard deviation, mmol/L

1.5 (1.0)

2.0 (1.0)^b

2.4 (1.3)^bc

2.2 (1.1)^b

Blood glucose CV

0.20 (0.15 to 0.26)

0.27 (0.22 to 0.34)^b

0.32 (0.25 to 0.39)^bc

0.31 (0.25 to 0.38)^b

Blood glucose CV >0.20

715/1,428 (50%)

735/873 (84%)^b

235/253 (93%)^bc

452/479 (94%)^b

Total insulin dose, IU

121 (38 to 344)

348 (123 to 801)^b

442 (129 to 986)^b

534 (201 to 1109)^b

Daily insulin dose, IU/day

19 (4 to 41)

34 (15 to 58)^b

35 (17 to 59)^b

38 (20 to 61)^b

Days with insulin

5 (3 to 11)

9 (4 to 17)^b

10 (5 to 20)^bc

12 (6 to 22)^b

Number of blood glucose measurements

28 (16 to 56)

44 (24 to 80)^b

52 (28 to 104)^bc

50 (32 to 108)^b

Number of moderate hypoglycemia

2 (1 to 3)

3 (1 to 6)

4 (3 to 6)

Number of severe hypoglycemia

–

–

1 (1 to 2)

0 (0 to 1)

Number of hypoglycemic events (any type)

–

2 (1 to 3)

5 (3 to 8)

4 (3 to 7)

Hypoglycemic events (any type) ≥3

–

286 (33%)

197 (77%)

482 (100%)