Variables | No hypoglycemia | Moderate hypoglycemia | Severe hypoglycemia | Multiple hypoglycemic events | |
---|---|---|---|---|---|
(n =1,474) | (n =874) | (n =253) | (n =482) | ||
Age, yr | 61 (17) | 63 (16) | 62 (15) | 63 (15) | |
Male sex, n (%) | 963/1,474 (65) | 553/874 (63) | 163/253 (64) | 320/482 (65) | |
Weight, kg | 80 (21) | 75 (18)b | 74 (20)b | 74 (18)b | |
Body mass index, kg/m2 | 27.5 (6.7) | 26.2 (5.9)b | 25.6 (6.1)b | 25.9 (6.0) | |
SAPS II score | 46 (34 to 61) | 52 (40 to 67)b | 59 (46 to 74)bc | 65 (55 to 75)b | |
SOFA score | 7 (4 to 10) | 8 (5 to 11)b | 10 (7 to 13)bc | 10 (7 to 12)b | |
McCabe score | 1 (1 to 2) | 1 (1 to 2) | 1 (1 to 2) | 1 (1 to 2) | |
Type of patient | |||||
Medical | 872/1,474 (59) | 161/874 (60) | 161/253 (64) | 281/482 (60) | |
Scheduled surgery | 457/1,474 (31) | 75/874 (29) | 75/253 (30) | 158/482 (30) | |
Emergency surgery | 145/1,474 (10) | 17/874 (11) | 17/253 (7) | 53/482 (10) | |
History of diabetes mellitus, n (%) | 266/1,474 (18) | 189/874 (22) | 70/253 (28)b | 131/482 (27) | |
Type 1 diabetes, n (%) | 38/1,474 (3) | 32/874 (4) | 14/253 (6) | 22/481 (5) | |
Type 2 diabetes, n (%) | 228/1,474 (15) | 157/874 (18) | 55/253 (22) | 108/481 (22) | |
Not determined | |||||
Previous treatment | 118/1,474 (5) | 21/873 (8) | 21/253 (8) | 35/482 (7) | |
Insulin, n (%) | 114/1,474 (5) | 18/873 (7) | 18/253 (7) | 28/482 (6) | |
Antidiabetic drugs, n (%) | |||||
Plasma creatinine, μmol/L | 133 (140) | 150 (133) | 166 (158)b | 169 (147)b | |
Initial treatment in the ICU | |||||
Mechanical ventilation | 1,273/1,430 (89) | 803/873 (92) | 240/253 (95)b | 453/482 (94)b | |
Catecholamines | 708/1,428 (50) | 533/253 (61)b | 195/253 (77)bc | 353/482 (73) | |
Renal replacement therapy | 119/1,428 (8) | 123/253 (14)b | 54/253 (21)bc | 96/482 (20)b | |
Antibiotics | 924/1,428 (65) | 597/253 (68) | 180/253 (71) | 351/482 (73) | |
Blood glucose control | |||||
Conventional | 900/1,474 (61) | 305/874 (35)b | 79/253 (31)b | 126/482 (26)b | |
Computerized | 574/1,474 (39) | 569/874 (65)b | 174/253 (69)b | 356/482 (74)b | |
Treatment-free days | |||||
Mechanical ventilation | 21 (0 to 26) | 14 (0 to 23)b | 0 (0 to 18)bc | 1 (0 to 18)b | |
Catecholamines | 26 (17 to 28) | 23 (0 to 27)b | 15 (0 to 24)bc | 18 (0 to 25)b | |
Renal replacement therapy | 28 (21 to 28) | 28 (0 to 28)b | 15 (0 to 28)bc | 24 (0 to 28)b | |
ICU-free days | 20 (0 to 25) | 12 (0 to 12)b | 0 (0 to 17)bc | 0 (0 to 117)b | |
Mortality | |||||
Day 28 | 315/1,474 (21) | 222/874 (25)b | 100/253 (39)bc | 162/482 (34)b | |
Day 90 | 407/1,474 (28) | 315/874 (36)b | 137/253 (54)bc | 248/482 (51)b |