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Table 1 Characteristics of the one-year survivors and non-survivors among critically ill patients with acute kidney injury within 24 hours of ICU admission

From: Predicting one-year mortality of critically ill patients with early acute kidney injury: data from the prospective multicenter FINNAKI study

 

Data

Survivors n = 466

Data

Non-survivors n = 308

P

Age, years

466

62.0 (53.0-72.0)

308

70.0 (61.0-79.0)

<0.001

Gender, male

466

307 (65.9)

308

199 (64.6)

0.716

Body mass index, kg/m2

465

27.8 (24.3-32.3)

306

26.5 (23.9-30.5)

<0.001

Hypertension

465

249 (53.5)

306

175 (57.2)

0.320

Systolic heart failure

460

39 (8.5)

300

58 (19.3)

<0.001

Arteriosclerosis

462

58 (12.6)

303

62 (20.5)

0.003

Chronic obstructive pulmonary disease

463

39 (8.4)

304

36 (11.8)

0.119

Diabetes mellitus

466

132 (28.3)

307

71 (23.1)

0.108

Malignancy

462

40 (8.7)

303

60 (19.8)

<0.001

Chronic kidney disease

463

37 (8.0)

306

43 (14.1)

0.007

Chronic liver disease

463

17 (3.6)

301

27 (9.0)

0.002

Immunosuppression

442

20 (4.5)

288

28 (9.7)

0.006

Number of co-morbidities

466

1.0 (0.0-2.0)

308

2.0 (1.0-3.0)

<0.001

 0 co-morbidity

466

146 (31.3)

308

50 (16.2)

<0.001

 1-2 co-morbidities

466

223 (47.9)

308

154 (50.0)

0.559

 ≥3 co-morbidities

466

97 (20.8)

308

104 (33.8)

<0.001

Premorbid functional performance preceding the acute illness

<0.001

 Normal or disabled to work but no need for assistance

465

405 (87.1)

308

238 (77.3)

<0.001

 Some assistance required or totally dependent on assistance

465

60 (12.9)

308

70 (22.7)

<0.009

Prior to ICU admission

 Hypotension prior to ICU admissiona

454

154 (33.9)

300

150 (50.0)

<0.001

 Resuscitation prior to ICU admissionb

466

34 (7.3)

305

55 (18.0)

<0.001

 Lactate prior to ICU admission, mmol/l

308

2.8 (1.5-5.3)

191

3.6 (1.5-8.1)

0.027

 pH prior to ICU admission

369

7.30 (7.19-7.38)

224

7.27 (7.14-7.36)

0.111

 Base excess prior to ICU admission, mmol/l

366

−6.7 (−12.5-(−2.5))

221

−7.8 (−14.4-(−3.5))

0.084

 Creatinine prior to ICU admission, μmol/l

431

136.0 (82.0-254.0)

285

141.0 (90.0-220.0)

0.794

 Platelets prior to ICU admission, E9/l

437

209.0 (141.5-282.5)

284

175.5 (101.3-266.8)

0.001

Admission type according to SAPS II

 Scheduled surgical

466

23 (4.9)

308

2 (0.6)

0.001

 Unscheduled surgical

466

126 (27.0)

308

65 (21.1)

0.061

 Medical

466

317 (68.0)

308

241 (78.2)

0.002

SAPS II, points

466

41.0 (32.0-51.0)

308

60.0 (47.0-73.0)

<0.001

SOFA D1, points

466

8.0 (6.0-11.0)

308

11.0 (9.0-14.0)

<0.001

SOFA D3, points

259

7.0 (1.0-14.0)

138

9.0 (2.48-17.0)

<0.001

Number of OF on D3c

255

1.0 (0.0-3.0)

138

2.0 (0.0-4.5)

<0.001

 0-1 OFc

255

174 (66.9)

138

65 (47.1)

<0.001

 2 OFc

255

61 (23.5)

138

39 (28.3)

0.29

 3 OFc

255

18 (6.9)

138

24 (17.4)

0.001

 ≥4 OFc

255

(0.8)

138

10 (7.2)

<0.001

∆OFc,d

255

−1.0 (−3.0-1.0)

138

0 (−3.0-1.5)

0.068

During the first 3 ICU days

 KDIGO stage 1

466

177 (38.0)

308

96 (31.2)

0.052

 KDIGO stage 2

466

110 (23.6)

308

70 (22.7)

0.777

 KDIGO stage 3 without RRT

466

64 (13.7)

308

49 (15.9)

0.402

 RRT

466

115 (24.7)

308

93 (30.2)

0.090

 Mechanical ventilation

466

293 (62.9)

308

248 (80.5)

<0.001

 Severe sepsis

466

184 (39.5)

308

142 (46.1)

0.068

Length of stay (days)

 ICU

466

3.4 (1.9-5.8)

308

2.7 (1.1-5.9)

0.001

 Hospital

466

13.0 (8.0-23.0)

308

8.0 (3.0-18.8)

<0.001

  1. aHypotension was defined as systolic blood pressure <90 mmHg for 1 hour within 48 hours prior to ICU admission; bresuscitation was defined as haemodynamic collapse requiring cardiopulmonary resuscitation, defibrillation or administration of epinephrine within 48 hours prior to ICU admission; cpatients with ICU stay for at least 3 days (n = 398); d∆OF was defined as the difference in the number of organ failures on D3 versus D1. ICU, intensive care unit; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; KDIGO, Kidney Disease: Improving Global Outcomes; RRT, renal replacement therapy; D1/D3 the first or third day on the ICU.
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