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Table 1 Characteristics of the one-year survivors and non-survivors among critically ill patients with acute kidney injury within 24 hours of ICU admission

From: Predicting one-year mortality of critically ill patients with early acute kidney injury: data from the prospective multicenter FINNAKI study

  Data Survivors n = 466 Data Non-survivors n = 308 P
Age, years 466 62.0 (53.0-72.0) 308 70.0 (61.0-79.0) <0.001
Gender, male 466 307 (65.9) 308 199 (64.6) 0.716
Body mass index, kg/m2 465 27.8 (24.3-32.3) 306 26.5 (23.9-30.5) <0.001
Hypertension 465 249 (53.5) 306 175 (57.2) 0.320
Systolic heart failure 460 39 (8.5) 300 58 (19.3) <0.001
Arteriosclerosis 462 58 (12.6) 303 62 (20.5) 0.003
Chronic obstructive pulmonary disease 463 39 (8.4) 304 36 (11.8) 0.119
Diabetes mellitus 466 132 (28.3) 307 71 (23.1) 0.108
Malignancy 462 40 (8.7) 303 60 (19.8) <0.001
Chronic kidney disease 463 37 (8.0) 306 43 (14.1) 0.007
Chronic liver disease 463 17 (3.6) 301 27 (9.0) 0.002
Immunosuppression 442 20 (4.5) 288 28 (9.7) 0.006
Number of co-morbidities 466 1.0 (0.0-2.0) 308 2.0 (1.0-3.0) <0.001
 0 co-morbidity 466 146 (31.3) 308 50 (16.2) <0.001
 1-2 co-morbidities 466 223 (47.9) 308 154 (50.0) 0.559
 ≥3 co-morbidities 466 97 (20.8) 308 104 (33.8) <0.001
Premorbid functional performance preceding the acute illness <0.001
 Normal or disabled to work but no need for assistance 465 405 (87.1) 308 238 (77.3) <0.001
 Some assistance required or totally dependent on assistance 465 60 (12.9) 308 70 (22.7) <0.009
Prior to ICU admission
 Hypotension prior to ICU admissiona 454 154 (33.9) 300 150 (50.0) <0.001
 Resuscitation prior to ICU admissionb 466 34 (7.3) 305 55 (18.0) <0.001
 Lactate prior to ICU admission, mmol/l 308 2.8 (1.5-5.3) 191 3.6 (1.5-8.1) 0.027
 pH prior to ICU admission 369 7.30 (7.19-7.38) 224 7.27 (7.14-7.36) 0.111
 Base excess prior to ICU admission, mmol/l 366 −6.7 (−12.5-(−2.5)) 221 −7.8 (−14.4-(−3.5)) 0.084
 Creatinine prior to ICU admission, μmol/l 431 136.0 (82.0-254.0) 285 141.0 (90.0-220.0) 0.794
 Platelets prior to ICU admission, E9/l 437 209.0 (141.5-282.5) 284 175.5 (101.3-266.8) 0.001
Admission type according to SAPS II
 Scheduled surgical 466 23 (4.9) 308 2 (0.6) 0.001
 Unscheduled surgical 466 126 (27.0) 308 65 (21.1) 0.061
 Medical 466 317 (68.0) 308 241 (78.2) 0.002
SAPS II, points 466 41.0 (32.0-51.0) 308 60.0 (47.0-73.0) <0.001
SOFA D1, points 466 8.0 (6.0-11.0) 308 11.0 (9.0-14.0) <0.001
SOFA D3, points 259 7.0 (1.0-14.0) 138 9.0 (2.48-17.0) <0.001
Number of OF on D3c 255 1.0 (0.0-3.0) 138 2.0 (0.0-4.5) <0.001
 0-1 OFc 255 174 (66.9) 138 65 (47.1) <0.001
 2 OFc 255 61 (23.5) 138 39 (28.3) 0.29
 3 OFc 255 18 (6.9) 138 24 (17.4) 0.001
 ≥4 OFc 255 (0.8) 138 10 (7.2) <0.001
∆OFc,d 255 −1.0 (−3.0-1.0) 138 0 (−3.0-1.5) 0.068
During the first 3 ICU days
 KDIGO stage 1 466 177 (38.0) 308 96 (31.2) 0.052
 KDIGO stage 2 466 110 (23.6) 308 70 (22.7) 0.777
 KDIGO stage 3 without RRT 466 64 (13.7) 308 49 (15.9) 0.402
 RRT 466 115 (24.7) 308 93 (30.2) 0.090
 Mechanical ventilation 466 293 (62.9) 308 248 (80.5) <0.001
 Severe sepsis 466 184 (39.5) 308 142 (46.1) 0.068
Length of stay (days)
 ICU 466 3.4 (1.9-5.8) 308 2.7 (1.1-5.9) 0.001
 Hospital 466 13.0 (8.0-23.0) 308 8.0 (3.0-18.8) <0.001
  1. aHypotension was defined as systolic blood pressure <90 mmHg for 1 hour within 48 hours prior to ICU admission; bresuscitation was defined as haemodynamic collapse requiring cardiopulmonary resuscitation, defibrillation or administration of epinephrine within 48 hours prior to ICU admission; cpatients with ICU stay for at least 3 days (n = 398); d∆OF was defined as the difference in the number of organ failures on D3 versus D1. ICU, intensive care unit; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; KDIGO, Kidney Disease: Improving Global Outcomes; RRT, renal replacement therapy; D1/D3 the first or third day on the ICU.