Table 4 Clinical relevance of the NF-κB gene polymorphisms in patients with major trauma
SNPs | Genotype | Number | Age, years | Sex, male/female, n | ISS | Sepsis, n (%) | MOD score |
|---|---|---|---|---|---|---|---|
rs28362491 | II | 245 | 40.5 ± 12.4 | 145/100 | 22 ± 10.3 | 108 (44.1) | 5.0 ± 2.3 |
ID | 386 | 42 ± 13.6 | 306/80 | 21.9 ± 8.6 | 156 (40.4) | 4.9 ± 2.1 | |
DD | 122 | 40.2 ± 13.2 | 98/24 | 24 ± 10.5 | 47 (38.5) | 4.9 ± 2.5 | |
rs4648068 | AA | 231 | 39.6 ± 12.5 | 192/39 | 22.0 ± 10.5 | 98 (42.4) | 4.9 ± 2.0 |
AG | 370 | 42.5 ± 13.8 | 294/76 | 22.1 ± 8.5 | 153 (41.4) | 5.1 ± 2.4 | |
GG | 151 | 40.4 ± 13.2 | 116/35 | 23.2 ± 10.3 | 56 (37.1) | 4.5 ± 1.7 | |
rs7119750 | CC | 280 | 40.8 ± 13.30 | 222/58 | 22.3 ± 9.9 | 118 (42.1) | 5.0 ± 2.3 |
CT | 374 | 40.9 ± 13.2 | 306/68 | 22.5 ± 9.4 | 154 (41.2) | 4.9 ± 2.2 | |
TT | 94 | 43.9 ± 13.9 | 72/22 | 21.3 ± 8.9 | 38 (40.4) | 5.1 ± 2.2 | |
rs842647 | GG | 551 | 40.7 ± 13.0 | 438/113 | 22.4 ± 9.9 | 228 (41.4) | 5.0 ± 2.3 |
GA | 167 | 42.8 ± 14.4 | 135/32 | 22.1 ± 7.9 | 70 (41.9) | 4.8 ± 2.0 | |
AA | 15 | 43.2 ± 16.6 | 14/1 | 20.5 ± 10.2 | 2 (13.3) | 3.1 ± 1.1 | |
P-value | a1 | a2 |