| Organ failure (transient) | Organ failure (persistent) | P -value |
---|---|---|---|
(n = 20) | (n = 35) | ||
Age, years | 70.5 (46.5 to 80.3) | 54 (44 to 71) | 0.159 |
Gender, M/F, n | 10/10 | 24/11 | 0.173 |
BMI, kg/m2 | 26.5 ± 4.3 | 25.3 ± 3.6 | 0.300 |
Body weight, kg | 66.4 ± 12.7 | 69.3 ± 12.3 | 0.415 |
Etiology, alcohol/biliary/ERCP/others | 4/15/0/1 | 17/15/1/2 | 0.126 |
Leukocytes, ×109/l | 12.9 ± 5.6 | 13.20 ± 7.3 | 0.888 |
Hemoglobin, g/dl | 10.5 ± 2.6 | 10.30 ± 2.2 | 0.718 |
Platelets, ×109/l | 157.5 (104.5 to 240) | 112 (49 to 229) | 0.178 |
BUN, mg/dl | 16.5 (7.5 to 26) | 26.5 (14 to 50.5) | 0.011 |
Serum Creatinine, mg/dl | 0.9 (0.8 to 1.3) | 2.6 (1.1 to 3.8) | 0.003 |
Bilirubin, mg/dl | 1.5 (0.8 to 1.9) | 2.6 (1.2 to 8.0) | 0.081 |
INR | 1.2 (1.1 to 1.4) | 1.3 (1.2 to 1.6) | 0.044 |
Ranson score | 5 (4 to 5.5) | 6 (5 to 7) | 0.009 |
APACHE II score | 12 (10 to 17.8) | 22 (15 to 28) | <0.001 |
SOFA score | 4.5 (2 to 6) | 8 (6 to 12.3) | <0.001 |
Modified Marshall score | 3 (2 to 3) | 6.5 (4.8 to 10) | <0.001 |
Number of organ failures | 1 (1 to 1.8) | 2 (2 to 3) | <0.001 |
 Respiratory failure | 17 (85%) | 33 (94.3%) | 0.342 |
 Renal failure | 6 (30%) | 26 (4.3%) | 0.001 |
 Cardiovascular failure | 3 (15%) | 21 (60%) | 0.002 |
Infected necrosis | 0 (0%) | 17 (51.4%) | <0.001 |
Cholesterol, mg/dl | 131.5 (117 to 170) | 94 (83 to 135) | 0.017 |
Triglyceride, mg/dl | 144 (116 to 242) | 153 (103 to 290) | 0.868 |
HDL, mg/dl | 30 (17 to 36) | 8 (5 to 15) | <0.001 |
LDL, mg/dl | 66 (56 to 74) | 42 (30 to 77) | 0.029 |
APO A-I, mg/dl | 81 (69 to 100) | 48 (31 to 54) | <0.001 |
IL-6, pg/ml | 63.5 (43 to 136.5) | 211 (104 to 552) | 0.005 |
TNF-α pg/ml | 6.3 (2.9 to 15) | 12 (6.1 to 25) | 0.048 |
CRP, mg/l | 195.0 ± 91.4 | 188.3 ± 118.3 | 0.833 |
Hospital mortality | 0 (0%) | 13 (35.3%) | 0.002 |
ICU mortality | 0 (0%) | 9 (25.7%) | 0.019 |
28-day mortality | 0 (0%) | 11 (31.4%) | 0.004 |
ICU stay, days | 5 (3 to 9) | 11 (5.8 to 17.3) | 0.009 |