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Table 4 Patients’ demographic data and clinical characteristics stratified by persistent organ failure

From: Serum levels of apolipoprotein A-I and high-density lipoprotein can predict organ failure in acute pancreatitis

 

Organ failure (transient)

Organ failure (persistent)

P -value

(n = 20)

(n = 35)

Age, years

70.5 (46.5 to 80.3)

54 (44 to 71)

0.159

Gender, M/F, n

10/10

24/11

0.173

BMI, kg/m2

26.5 ± 4.3

25.3 ± 3.6

0.300

Body weight, kg

66.4 ± 12.7

69.3 ± 12.3

0.415

Etiology, alcohol/biliary/ERCP/others

4/15/0/1

17/15/1/2

0.126

Leukocytes, ×109/l

12.9 ± 5.6

13.20 ± 7.3

0.888

Hemoglobin, g/dl

10.5 ± 2.6

10.30 ± 2.2

0.718

Platelets, ×109/l

157.5 (104.5 to 240)

112 (49 to 229)

0.178

BUN, mg/dl

16.5 (7.5 to 26)

26.5 (14 to 50.5)

0.011

Serum Creatinine, mg/dl

0.9 (0.8 to 1.3)

2.6 (1.1 to 3.8)

0.003

Bilirubin, mg/dl

1.5 (0.8 to 1.9)

2.6 (1.2 to 8.0)

0.081

INR

1.2 (1.1 to 1.4)

1.3 (1.2 to 1.6)

0.044

Ranson score

5 (4 to 5.5)

6 (5 to 7)

0.009

APACHE II score

12 (10 to 17.8)

22 (15 to 28)

<0.001

SOFA score

4.5 (2 to 6)

8 (6 to 12.3)

<0.001

Modified Marshall score

3 (2 to 3)

6.5 (4.8 to 10)

<0.001

Number of organ failures

1 (1 to 1.8)

2 (2 to 3)

<0.001

 Respiratory failure

17 (85%)

33 (94.3%)

0.342

 Renal failure

6 (30%)

26 (4.3%)

0.001

 Cardiovascular failure

3 (15%)

21 (60%)

0.002

Infected necrosis

0 (0%)

17 (51.4%)

<0.001

Cholesterol, mg/dl

131.5 (117 to 170)

94 (83 to 135)

0.017

Triglyceride, mg/dl

144 (116 to 242)

153 (103 to 290)

0.868

HDL, mg/dl

30 (17 to 36)

8 (5 to 15)

<0.001

LDL, mg/dl

66 (56 to 74)

42 (30 to 77)

0.029

APO A-I, mg/dl

81 (69 to 100)

48 (31 to 54)

<0.001

IL-6, pg/ml

63.5 (43 to 136.5)

211 (104 to 552)

0.005

TNF-α pg/ml

6.3 (2.9 to 15)

12 (6.1 to 25)

0.048

CRP, mg/l

195.0 ± 91.4

188.3 ± 118.3

0.833

Hospital mortality

0 (0%)

13 (35.3%)

0.002

ICU mortality

0 (0%)

9 (25.7%)

0.019

28-day mortality

0 (0%)

11 (31.4%)

0.004

ICU stay, days

5 (3 to 9)

11 (5.8 to 17.3)

0.009

  1. Results are presented as mean ± SD, or median (IQR) unless otherwise stated. M male; F female; BMI body mass index; ERCP endoscopic retrograde cholangiopancreagraphy; BUN blood urea nitrogen; INR international normalized ratio; APACHE acute physiology and chronic health evaluation; SOFA sequential organ failure assessment; HDL high-density lipoprotein; LDL low-density lipoprotein; APO A-I apolipoprotein A-I; TNF tumor necrosis factor; CRP C-reactive protein.