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Table 4 Patients’ demographic data and clinical characteristics stratified by persistent organ failure

From: Serum levels of apolipoprotein A-I and high-density lipoprotein can predict organ failure in acute pancreatitis

  Organ failure (transient) Organ failure (persistent) P -value
(n = 20) (n = 35)
Age, years 70.5 (46.5 to 80.3) 54 (44 to 71) 0.159
Gender, M/F, n 10/10 24/11 0.173
BMI, kg/m2 26.5 ± 4.3 25.3 ± 3.6 0.300
Body weight, kg 66.4 ± 12.7 69.3 ± 12.3 0.415
Etiology, alcohol/biliary/ERCP/others 4/15/0/1 17/15/1/2 0.126
Leukocytes, ×109/l 12.9 ± 5.6 13.20 ± 7.3 0.888
Hemoglobin, g/dl 10.5 ± 2.6 10.30 ± 2.2 0.718
Platelets, ×109/l 157.5 (104.5 to 240) 112 (49 to 229) 0.178
BUN, mg/dl 16.5 (7.5 to 26) 26.5 (14 to 50.5) 0.011
Serum Creatinine, mg/dl 0.9 (0.8 to 1.3) 2.6 (1.1 to 3.8) 0.003
Bilirubin, mg/dl 1.5 (0.8 to 1.9) 2.6 (1.2 to 8.0) 0.081
INR 1.2 (1.1 to 1.4) 1.3 (1.2 to 1.6) 0.044
Ranson score 5 (4 to 5.5) 6 (5 to 7) 0.009
APACHE II score 12 (10 to 17.8) 22 (15 to 28) <0.001
SOFA score 4.5 (2 to 6) 8 (6 to 12.3) <0.001
Modified Marshall score 3 (2 to 3) 6.5 (4.8 to 10) <0.001
Number of organ failures 1 (1 to 1.8) 2 (2 to 3) <0.001
 Respiratory failure 17 (85%) 33 (94.3%) 0.342
 Renal failure 6 (30%) 26 (4.3%) 0.001
 Cardiovascular failure 3 (15%) 21 (60%) 0.002
Infected necrosis 0 (0%) 17 (51.4%) <0.001
Cholesterol, mg/dl 131.5 (117 to 170) 94 (83 to 135) 0.017
Triglyceride, mg/dl 144 (116 to 242) 153 (103 to 290) 0.868
HDL, mg/dl 30 (17 to 36) 8 (5 to 15) <0.001
LDL, mg/dl 66 (56 to 74) 42 (30 to 77) 0.029
APO A-I, mg/dl 81 (69 to 100) 48 (31 to 54) <0.001
IL-6, pg/ml 63.5 (43 to 136.5) 211 (104 to 552) 0.005
TNF-α pg/ml 6.3 (2.9 to 15) 12 (6.1 to 25) 0.048
CRP, mg/l 195.0 ± 91.4 188.3 ± 118.3 0.833
Hospital mortality 0 (0%) 13 (35.3%) 0.002
ICU mortality 0 (0%) 9 (25.7%) 0.019
28-day mortality 0 (0%) 11 (31.4%) 0.004
ICU stay, days 5 (3 to 9) 11 (5.8 to 17.3) 0.009
  1. Results are presented as mean ± SD, or median (IQR) unless otherwise stated. M male; F female; BMI body mass index; ERCP endoscopic retrograde cholangiopancreagraphy; BUN blood urea nitrogen; INR international normalized ratio; APACHE acute physiology and chronic health evaluation; SOFA sequential organ failure assessment; HDL high-density lipoprotein; LDL low-density lipoprotein; APO A-I apolipoprotein A-I; TNF tumor necrosis factor; CRP C-reactive protein.