Skip to main content

Table 3 Patients’ demographic data and clinical characteristics stratified by early organ failure

From: Serum levels of apolipoprotein A-I and high-density lipoprotein can predict organ failure in acute pancreatitis

  Organ failure No organ failure P -value
(n = 55) (n = 11)
Age, years 59 (45 to 76) 69 (45 to 92) 0.429
Gender, M/F, n 34/21 4/7 0.182
BMI, kg/m2 25.7 ± 3.8 26.2 ± 4.4 0.748
Body weight, kg 68.3 ± 12.2 65.7 ± 10.9 0.545
Etiology, alcohol/biliary/ERCP/others 21/30/1/3 4/7/0/0 0.815
Leukocytes, ×109/l 13.1 ± 6.6 9.1 ± 4.6 0.058
Hemoglobin, g/dl 10.4 ± 2.3 10.3 ± 1.5 0.936
Platelets, ×109/l 138 (72 to 229) 139.5 (58.5 to 247.3) 0.935
BUN, mg/dl 23 (12.5 to 41.5) 12 (7 to 22) 0.023
Serum Creatinine, mg/dl 1.5 (0.9 to 3.2) 0.7 (0.6 to 0.9) <0.001
Bilirubin, mg/dl 1.6 (1.1 to 5.4) 1.5 (1 to 4) 0.642
INR 1.2 (1.1 to 1.5) 1.05 (1 to 1.13) 0.002
Ransons score 5.5 (4 to 7) 4 (3 to 4) 0.001
APACHE II score 18 (11 to 25.5) 14 (10 to 15) 0.028
SOFA score 6 (4.3 to 9.8) 3 (2 to 5) 0.005
Modified Marshall score 5 (3 to 7.25) 1 (0 to 1) <0.001
Infected necrosis, n 18 (32.7%) 0 (0%) 0.028
Cholesterol, mg/dl 117 (83 to 142) 151 (109 to 172) 0.046
Triglyceride, mg/dl 148 (105 to 285) 132 (92 to 167) 0.242
HDL, mg/dl 15 (6 to 22) 24 (19 to 33) 0.010
LDL, mg/dl 56 (37 to 75) 82 (65 to 100) 0.005
APO A-I, mg/dl 54 (41 to 74) 78 (55 to 96) 0.020
IL-6, pg/ml 129 (54 to 251.5) 29 (10.4 to 101.5) 0.005
TNF-α, pg/ml 10.8 (4.7 to 23) 2.9 (1.1 to 3.7) 0.001
CRP, mg/l 190.6 ± 108.9 111.0 ± 90.4 0.027
Hospital mortality 13 (23.6%) 0 (0%) 0.104
ICU mortality 9 (16.4%) 0 (0%) 0.337
28-day mortality 11 (20%) 0 (0%) 0.188
ICU stay, days 8 (5 to 14.5) 5 (5 to 11) 0.510
  1. Results are presented as mean ± SD, or median (IQR) unless otherwise stated. M, male; F, female; BMI, body mass index; ERCP, endoscopic retrograde cholangiopancreagraphy; BUN, blood urea nitrogen; INR, international normalized ratio; APACHE, acute physiology and chronic health evaluation; SOFA, sequential organ failure assessment; HDL, high-density lipoprotein; LDL, low-density lipoprotein; APO A-I, apolipoprotein A-I; CRP C-reactive protein.