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Table 2 Comparison between groups for operative characteristics and outcomes after adjustment for confounding variablesa

From: Efficacy and safety of 6% hydroxyethyl starch 130/0.4 (Voluven) for perioperative volume replacement in children undergoing cardiac surgery: a propensity-matched analysis

Variables

HES group

HA group

Adjusted P -value

(nos = 1007)

(nos = 322)

(nm = 1007)

(nm = 1007)

Surgery duration (min)

217.4 (67.8)

227.5 (98.5)

0.082

CPB duration (min)

110.8 (45.4)

117.6 (53.8)

0.013

Aortic clamping (%)

904 (89.8)

303 (94.4)

0.100

Minimum temperature during CPB (°C)

30.4 (2.9)

28.4 (3.8)

<0.001b

Priming volume (ml∙kg−1)

65.7 (34.7)

111.5 (54.7)

<0.001b

Degree of hemodilution (%)c

80.1 (36.9)

136.4 (58.2)

<0.001b

MUF (%)

921 (91.6)

919 (91.4)

0.41

MUF (ml∙kg−1)

29.9 (16.5)

31.3 (17.6)

0.86

Exposure to blood products (%)

639 (63.5)

801 (79.5)

<0.001b

Reexploration for bleeding (%)

7 (0.7)

6 (0.6)

0.79

ICU infection (%)

438 (43.6)

445 (44.3)

0.57

Neurological disorder (%)

27 (2.7)

37 (3.7)

0.53

Postoperative cardiac assistance (%)

13 (1.3)

20 (2.0)

0.90

Renal replacement therapy (%)

11 (1.1)

14 (1.4)

0.17

ICU length of stay (days)

7.5 (10.0)

7.0 (6.7)

0.41

Length of hospital stay (days)

19.7 (16.6)

20.1 (16.2)

0.10

In-hospital mortality (%)

21 (2.1)

7 (2.3)

0.24

  1. aCPB, Cardiopulmonary bypass; HA, Human albumin; HES, Hydroxyethyl starch; ICU: intensive care unit; MUF, Modified ultrafiltration; nm, Number of matched observations; nos, Number of observations in the original sample. bVariable significantly different between the two groups after applying the Bonferroni correction. cDegree of hemodilution is presented as the mean percentage hemodilution with standard deviation in parentheses.