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Table 3 Parameters of endothelial condition in critically ill patients before and after a transfusion of fresh frozen plasma (12 ml/kg)

From: Effect of transfusion of fresh frozen plasma on parameters of endothelial condition and inflammatory status in non-bleeding critically ill patients: a prospective substudy of a randomized trial

 

Before FFP

After FFP

P value

vWF-Ag

474.0 (331.5–639.5)

423.0 (313.5–539.0)

<0.001

Factor VIII

246.4 (203.6–364.4)

246.40 (321.2)

<0.01

ADAMTS13

23.9 (15.8)

31.7 (17.9)

<0.001

Syndecan-1

674.6 (132.2–1689.8)

565.1 (126.8–1175.7)

<0.01

  1. Data expressed as median (IQR) or mean (SD). FFP, fresh frozen plasma; vWF:Ag, von Willebrand factor antigen; ADAMTS13, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13; IQR, interquartile range; SD, standard deviation.
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Critical Care

ISSN: 1364-8535