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Table 5 Unadjusted and adjusted associations between predictors and odds of survival to hospital discharge

From: Exposure to high concentrations of inspired oxygen does not worsen lung injury after cardiac arrest

Baseline predictor

Odds ratio (OR)

P -value

 

Unadjusted OR (95% CI)

 

FiO2 AUC

0.90 (0.82 to 0.98)

0.02

Age

1.02 (1.00 to 1.04)

0.10

Male sex

0.66 (0.19 to 1.22)

0.19

Out-of-hospital arrest

0.66 (0.36 to 1.21)

0.18

Arrest rhythm VT/VF

1.62 (0.87 to 3.03)

0.13

Received TH

0.24 (0.13 to 0.48)

<0.001

PCAC

  

 1

Reference

Reference

 2

0.67 (0.26 to 1.72)

0.41

 3

0.32 (0.11 to 0.94)

0.04

 4

0.07 (0.02 to 0.22)

<0.001

First P:F ratio

1.00 (1.00 to 1.00)

0.38

Initial pulmonary compliance

0.99 (0.97 to 1.02)

0.68

Initial SOFA-respiratory score

 

0.23

 0

Reference

Reference

 1

0.38 (0.13 to 1.11)

0.08

 2

0.94 (0.34 to 2.63)

0.91

 3

0.77 (0.29 to 2.02)

0.59

 4

1.13 (0.40 to 3.19)

0.81

Initial SOFA-cardiovascular score

 

<0.01

 0

Reference

Reference

 1

0.95 (0.34 to 2.70)

0.94

 2

0.09 (0.01 to 0.71)

0.02

 3

0.31 (0.13 to 0.77)

0.01

 4

0.40 (0.17 to 0.92)

0.03

Initial CVI

0.82 (0.69 to 0.98)

0.03

Time to first vent wean

1.04 (1.00 to 1.10)

0.08

Number of vent weans in 24 h

0.79 (0.64 to 0.98)

0.03

 

Adjusted OR (95% CI)

 

FiO2 AUC

0.86 (0.76 to 0.97)

0.02

Age

1.01 (0.98 to 1.04)

0.38

Male sex

0.52 (0.23 to 1.18)

0.12

Out-of-hospital arrest

1.48 (0.52 to 4.23)

0.46

Arrest rhythm VT/VF

1.53 (0.62 to 3.77)

0.35

Received TH

0.19 (0.07 to 0.58)

<0.01

PCAC

  

 1

Reference

Reference

 2

1.25 (0.33 to 4.79)

0.74

 3

0.91 (0.24 to 3.51)

0.89

 4

0.13 (0.03 to 0.58)

<0.01

Initial SOFA-cardiovascular score

  

 0

Reference

Reference

 1

0.62 (0.14 to 2.69)

0.52

 2

0.05 (0.00 to 0.71)

0.03

 3

0.23 (0.04 to 1.31)

0.10

 4

0.12 (0.01 to 1.73)

0.12

Initial CVI

1.29 (0.73 to 2.26)

0.38

Time to first vent wean

0.78 (0.95 to 1.10)

0.13

Number of vent weans in 24 h

1.03 (0.58 to 1.07)

0.49

  1. FiO2, fraction of inspired oxygen; AU, area under the curve; VT/VF, ventricular tachycardia or ventricular fibrillation; TH, therapeutic hypothermia; PCAC, Pittsburgh cardiac arrest category; P:F, partial pressure of arterial oxygen to fraction of inspired oxygen; SOFA, sequential organ failure assessment; CVI, cumulative vasopressor index.