Table 4 Optimum thresholds and respective test accuracy parameters for predicting (a) acute traumatic coagulopathy (ATC) defined as INR >1.2 and (b) massive transfusion (MT) (defined as ≥10 units of PRBC)
Test parameter | Optimum threshold | Detection rate | False positive rate | PPV | NPV | |||||
|---|---|---|---|---|---|---|---|---|---|---|
(a) | ||||||||||
EXTEM CA5 | ≤37 | (34-39) | 66.3 | (55.1-76.3) | 18.8 | (15.9-21.9) | 29.9 | (23.4-37.1) | 95.2 | (93.2-96.8) |
FIBTEM CA5 | ≤8 | (5-8) | 67.5 | (55.9-77.8) | 20.7 | (17.7-23.9) | 26.9 | (20.8-33.8) | 95.6 | (93.5-97.1) |
Fibrinogen | ≤1.61 | (1.36-1.9) | 73.6 | (63.0-82.4) | 11.5 | (9.2-14.1) | 45.1 | (36.7-53.6) | 96.3 | (94.5-97.7) |
Platelet count | ≤199 | (128-199) | 61.7 | (46.4-75.5) | 29.9 | (26.6-33.4) | 11.9 | (8.1-16.7) | 96.5 | (94.6-97.9) |
(b) | ||||||||||
EXTEM CA5 | ≤40 | (32-40) | 72.7 | (57.2-85.0) | 31.3 | (28.0-34.8) | 12.2 | (8.5-16.8) | 97.7 | (96.0-98.8) |
FIBTEM CA5 | ≤9 | (6-9) | 77.5 | (61.5-89.2) | 32.8 | (29.4-36.4) | 11.4 | (7.9-15.8) | 98.2 | (96.6-99.2) |
Fibrinogen | ≤1.90 | (1.39-2.18) | 77.8 | (62.9-88.8) | 29.7 | (26.4-30.1) | 14.0 | (9.9-18.9) | 98.1 | (96.5-99.1) |
INR | ≥1.13 | (1.0-1.16) | 70.2 | (55.1-82.7) | 19.0 | (16.2-22.1) | 19.2 | (13.6-25.9) | 97.7 | (96.2-98.7) |
Platelet count | ≤174 | (159-182) | 52.8 | (41.9-63.5) | 14.8 | (12.2-17.7) | 32.2 | (24.7-40.4) | 93.1 | (90.8-95.0) |