|
Test parameter
|
Optimum threshold
|
Detection rate
|
False positive rate
|
PPV
|
NPV
|
|---|
|
(a)
| |
|
EXTEM CA5
|
≤37
|
(34-39)
|
66.3
|
(55.1-76.3)
|
18.8
|
(15.9-21.9)
|
29.9
|
(23.4-37.1)
|
95.2
|
(93.2-96.8)
|
|
FIBTEM CA5
|
≤8
|
(5-8)
|
67.5
|
(55.9-77.8)
|
20.7
|
(17.7-23.9)
|
26.9
|
(20.8-33.8)
|
95.6
|
(93.5-97.1)
|
|
Fibrinogen
|
≤1.61
|
(1.36-1.9)
|
73.6
|
(63.0-82.4)
|
11.5
|
(9.2-14.1)
|
45.1
|
(36.7-53.6)
|
96.3
|
(94.5-97.7)
|
|
Platelet count
|
≤199
|
(128-199)
|
61.7
|
(46.4-75.5)
|
29.9
|
(26.6-33.4)
|
11.9
|
(8.1-16.7)
|
96.5
|
(94.6-97.9)
|
|
(b)
|
|
EXTEM CA5
|
≤40
|
(32-40)
|
72.7
|
(57.2-85.0)
|
31.3
|
(28.0-34.8)
|
12.2
|
(8.5-16.8)
|
97.7
|
(96.0-98.8)
|
|
FIBTEM CA5
|
≤9
|
(6-9)
|
77.5
|
(61.5-89.2)
|
32.8
|
(29.4-36.4)
|
11.4
|
(7.9-15.8)
|
98.2
|
(96.6-99.2)
|
|
Fibrinogen
|
≤1.90
|
(1.39-2.18)
|
77.8
|
(62.9-88.8)
|
29.7
|
(26.4-30.1)
|
14.0
|
(9.9-18.9)
|
98.1
|
(96.5-99.1)
|
|
INR
|
≥1.13
|
(1.0-1.16)
|
70.2
|
(55.1-82.7)
|
19.0
|
(16.2-22.1)
|
19.2
|
(13.6-25.9)
|
97.7
|
(96.2-98.7)
|
|
Platelet count
|
≤174
|
(159-182)
|
52.8
|
(41.9-63.5)
|
14.8
|
(12.2-17.7)
|
32.2
|
(24.7-40.4)
|
93.1
|
(90.8-95.0)
|
- INR, international normalized ratio; PRBC, packed red blood cells; PPV, positive predictive value; NPV, negative predictive value; CA5, clot amplitude after 5 minutes.
