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Table 3 ROC analyses of parameters predicting acute traumatic coagulopathy (ATC) and massive transfusion (MT)

From: Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: an international prospective validation study

 

ATC

 

MT

 
 

AUC

(95% CI)

AUC

(95% CI)

EXTEM CT (s)

0.73

(0.70-0.76)

0.68

(0.65-0.71)

EXTEM CA5 (mm)

0.79

(0.76-0.81)

0.75

(0.72-0.78)

EXTEM CA10 (mm)

0.78

(0.75-0.81)

0.75

(0.72-0.78)

EXTEM CFT (s)

0.77

(0.74-0.80)

0.73

(0.70-0.76)

EXTEM Alpha (°)

0.78

(0.75-0.81)

0.73

(0.69-0-76)

EXTEM MCF (mm)

0.73

(0.70-0.76)

0.70

(0.67-0.73)

FIBTEM CT (s)

0.72

(0.68-0.75)

0.65

(0.62-0.69)

FIBTEM CA5 (mm)

0.80

(0.77-0.83)

0.78

(0.74-0.81)

FIBTEM CA10 (mm)

0.79

(0.76-0.82)

0.76

(0.73-0.79)

FIBTEM MCF (mm)

0.77

(0.74-0.80)

0.76

(0.73-0.79)

Fibrinogen concentration

0.87*

(0.84-0.89)

0.81

(0.78-0.83)

INR

N/A

N/A

0.82

(0.79-0.84)

Platelet count

0.74

(0.70-0.77)

0.70

(0.66-0.73)

  1. ATC, acute traumatic coagulopathy defined as INR >1.2. MT, massive transfusion defined as 10 or more packed red blood cells. All AUCs values are statistically different from 0.5 with a P ≤0.001. *AUC is significantly larger than the AUC of the ROTEM parameters (P = 0.002 for difference to FIBTEM CA5). ROC, receiver operating characteristics; AUC, area under the curve; CT, clotting time; CA5, clot amplitude after 5 minutes; CA10, clot amplitude after 10 minutes; CFT, clot formation time; MCF, maximum clot firmness; INR, international normalized ratio.