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Figure 2 | Critical Care

Figure 2

From: β1-adrenoceptor stimulation promotes LPS-induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation

Figure 2

Dobutamine (DOB) enhances caspase-8 and caspase-9 activation in lipopolysaccharide (LPS)-treated adult mouse cardiomyocytes. Caspase-8 (A) and caspase-9 (B) activities were detected in cardiomyocytes treated with 0.02 μM DOB or/and 10 ng/mL LPS for 6, 12 or 24 hours. Mean ± standard error of the mean (n = 4). * P <0.05 compared with the control group; ## P <0.01 compared with the LPS group.

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Critical Care

ISSN: 1364-8535