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Table 2 Comparison of clinical characteristics of patients with acute respiratory distress syndrome (ARDS) according to survival

From: The ratio of Th17/Treg cells as a risk indicator in early acute respiratory distress syndrome

Variables Non-survivors (n = 32) Survivors (n = 47) P -value
Age, years 53.38 ± 13.80 56.72 ± 15.27 0.323
Gender, male/female, n 17/15 26/21 0.848
BMI, kg/m2 24.34 ± 4.12 24.69 ± 4.29 0.716
APACH II score 26 (22 to 27) 21 (19 to 23) <0.001
SOFA score 12 (11 to 13) 10 (9 to 12) <0.001
Lung injury score 2.6 (2.2 to 3.1) 2.1 (2.0 to 2.7) 0.002
PaO2/FiO2, mmHg 111 (67 to 183) 157 (84 to 231) 0.037
CRP, mg/L 138.59 (123.40 to 165.47) 135.64 (116.53 to 156.76) 0.413
PCT, ng/mL 1.64 (1.33 to 2.05) 1.38 (1.07 to 1.67) 0.031
Leukocytes, 109/L 13.2 (11.5 to 15.8) 12.7 (10.8 to 14.5) 0.507
Monocytes, 109/L 1.07 (0.99 to 1.28) 1.04 (0.88 to 1.18) 0.124
Lymphocytes, 109/L 5.76 (4.80 to 6.61) 5.10 (4.16 to 6.21) 0.044
Th17 cells, % of CD4+ 4.84 (4.25 to 6.76) 4.01 (3.56 to 5.34) <0.001
Treg cells, % of CD4+ 5.33 (4.98 to 5.94) 5.46 (4.98 to 6.12) 0.583
Th17/Treg ratio 0.98 ± 0.20 0.78 ± 0.15 <0.001
IL-6, pg/mL 790.68 ± 66.95 736.30 ± 63.80 <0.001
IL-17, pg/mL 229.09 ± 77.18 179.50 ± 53.25 0.003
IL-10, pg/mL 128.48 ± 21.87 133.04 ± 18.53 0.321
TGF-β, pg/mL 216.81 ± 55.44 205.23 ± 47.80 0.325
  1. Quantitative data with a normal distribution are presented as mean ± SD. Quantitative data with a non-normal distribution are presented as median (IQR). BMI, body mass index; APACHE, acute physiologic and chronic health evaluation; SOFA, sequential organ failure assessment; CRP, C-reactive protein; PCT, procalcitonin.