Table 2 Comparison of clinical characteristics of patients with acute respiratory distress syndrome (ARDS) according to survival
From: The ratio of Th17/Treg cells as a risk indicator in early acute respiratory distress syndrome
Variables | Non-survivors (n = 32) | Survivors (n = 47) | P -value |
|---|---|---|---|
Age, years | 53.38 ± 13.80 | 56.72 ± 15.27 | 0.323 |
Gender, male/female, n | 17/15 | 26/21 | 0.848 |
BMI, kg/m2 | 24.34 ± 4.12 | 24.69 ± 4.29 | 0.716 |
APACH II score | 26 (22 to 27) | 21 (19 to 23) | <0.001 |
SOFA score | 12 (11 to 13) | 10 (9 to 12) | <0.001 |
Lung injury score | 2.6 (2.2 to 3.1) | 2.1 (2.0 to 2.7) | 0.002 |
PaO2/FiO2, mmHg | 111 (67 to 183) | 157 (84 to 231) | 0.037 |
CRP, mg/L | 138.59 (123.40 to 165.47) | 135.64 (116.53 to 156.76) | 0.413 |
PCT, ng/mL | 1.64 (1.33 to 2.05) | 1.38 (1.07 to 1.67) | 0.031 |
Leukocytes, 109/L | 13.2 (11.5 to 15.8) | 12.7 (10.8 to 14.5) | 0.507 |
Monocytes, 109/L | 1.07 (0.99 to 1.28) | 1.04 (0.88 to 1.18) | 0.124 |
Lymphocytes, 109/L | 5.76 (4.80 to 6.61) | 5.10 (4.16 to 6.21) | 0.044 |
Th17 cells, % of CD4+ | 4.84 (4.25 to 6.76) | 4.01 (3.56 to 5.34) | <0.001 |
Treg cells, % of CD4+ | 5.33 (4.98 to 5.94) | 5.46 (4.98 to 6.12) | 0.583 |
Th17/Treg ratio | 0.98 ± 0.20 | 0.78 ± 0.15 | <0.001 |
IL-6, pg/mL | 790.68 ± 66.95 | 736.30 ± 63.80 | <0.001 |
IL-17, pg/mL | 229.09 ± 77.18 | 179.50 ± 53.25 | 0.003 |
IL-10, pg/mL | 128.48 ± 21.87 | 133.04 ± 18.53 | 0.321 |
TGF-β, pg/mL | 216.81 ± 55.44 | 205.23 ± 47.80 | 0.325 |