Table 5 Studies of ECMO for H1N1-associated ARDS reporting on ≤ 10 patients
From: Extracorporeal gas exchange for acute respiratory failure in adult patients: a systematic review
|  | Roncon [ 42 ] | D’Ancona [ 38 ] | Roch [ 41 ] | Hou [ 45 ] | Bonastre [ 47 ] | Turner [ 44 ] | Chan [ 37 ] | Freed [ 39 ] |
|---|---|---|---|---|---|---|---|---|
Country | Portugal | Italy | France | China | Spain | USA | Hong Kong | Canada |
Patients, n | 10 | 10 | 9 | 9 | 9 | 7 | 7 | 6 |
Study design | Case series | Case series | Case series | Case series | Case series | Case series | Case series | Case series |
Number of centers | 1 | 1 | 1 | 1 | 5 | 1 | 3 | 4 |
Age, years | 40 (36–47) | 36 (23–55) | 49 (26–57) | 31 ± 11 | 36 (28–42) | 24 (16–25) | 42 (39–50) | 33 ± 7 |
BMI, kg/m2 | – | 26 (21–48) | 30 (25–80) | – | – | 27 (26–29) | 26 (26–27) | 33 ± 7 |
Pregnant or postpartum | 1(10) | 0 (0) | 1 (11) | 4 (44) | – | 1 (14) | 0 (0) | – |
SOFA | – | – | 9 (8–10) | – | – | – | – | – |
Interval MV-ECMO, d | 6.5 (2.2–12.2) | – | 0.5 (0.25–4.0) | 6 (2–10) | 5 (2–7) | 6.0 (1.5–12.5) | – | 5.0 (2.5–8.3) |
Pre-ECMO parameter | Â | Â | Â | Â | Â | Â | Â | Â |
pH | 7.33 (7.28–7.38) | – | 7.17 (7.04–7.25) | – |  | – | 7.30 (7.19–7.36) | 7.31 ± 0.05 |
PaO2/FiO2, mmHg | 69 (56–84) | – | 52 (50–60) | 53 (45–64) | 66 (64–102) | 57 (51–62) | 56 (53–71) | 58 ± 17 |
Plateau pressure, mmHg | 35 (32–36) | – | 31 (30–35) | – | – | – | 33 (30–35)* | 44 ± 42* |
Lung injury score | 3.5 (3.3–3.8) | – | 3.6 (3.3–3.7) | 3.6 (3.25–3.75) | – | – | 3.8 (3.8–3.9) | – |
Any rescue therapy, % | 70 | 100 | – | – | – | 100 | 14 | 100 |
Nitric oxide, % | 60 | – | 67 | – |  | 100 | 0 | 67 |
Prone position, % | 10 | – | 22 | – |  | 0 | 14 | 33 |
Duration of ECMO, days | 22 (14–32) | – | 9 (4–14) | 18 (3–90) | 6 (5–22) | 13 (8–37) | 6 (6–10) | 15 (14–15) |
Mortality, n (%) | 4 (40) | 5 (50) | 5 (56) | 4 (44) | 5 (56) | 2 (28) | 1 (14) | 2 (33) |