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Table 3 Studies of ECMO for ARDS published before 1997 or including < 30 patients

From: Extracorporeal gas exchange for acute respiratory failure in adult patients: a systematic review

First author [ref] Design Prospective Setting Follow up Quality of the study ECMO patients Years Age, years Pre ECMO PaO 2 /FiO 2 , mmHg Length of ECMO, days Mortality, n (%)
Zapol [13] RCT Y Multi ICU discharge RCT4 42 1979 12 to 65 <83 <5 days 39 (92%)
Macha [76] Case series N Single Hospital discharge 33 1990–1995 36 ± 2 59 ± 5 6 ± 1 13 (39%)
Cordell-Smith [77] Case series N Single ICU discharge 28 1992–2000 27* 62* 6* 8 (29%)
Haneya [78] Case series Y Single ICU discharge 22 2010–2011 47 (36–61) 60 (46–75) 13 (8–19) 7 (32%)
Hodgson [66] Case series N Single 8 months 21£ 2009–2011 36 ± 12 69(50–105) 11 (4–16) 3 (14%)
Huang [79] Case series N Single ICU discharge 16 2003–2005 32 ± 22 54 ± 8 7 ± 4 6 (37%)
Isgrò [80] Case series Y Single Hospital discharge 12 2004–2009 35 ± 19 60 ± 11 6 (54%)
Oshima [81] Case series N Single ICU discharge 11 2003–2008 52 ± 24 90 ± 10 10 ± 9 5 (45%)
Bermudez [82] Case series N Single ICU discharge 11 2009–2010 34 (25–54) 45 (28–248) 3 (0–11) 5 (45%)
Goulon [83] Case series N Single 8 months 11 1973–1976 29 (22–37) 39 ± 12 3 (1–4) 9 (82%)
Park [84] Case series N Multi 60 days 10 2011 47 (14–71) 50 (36–56) 5 (3–32) 6 (60%)
Park [85] Case series N Single ICU discharge 9 2008–2011 56 (51–64) 57 ± 8 12 ± 6 10 (55%)
Huang [79] Case series N Single 11 (8–51) months 9 2004–2007 35 ± 10 49 (31–64) 6 (3–19) 7 (78%)
Rossaint [86] Case series N Single Hospital discharge 8 1993–1995 35 (24–49) 43 ± 4 8 ± 9 2 (25%)
  1. ICU: intensive care unit; Multi: multicenter; N: no; RCT: randomized controlled trial; Y: yes.
  2. Data are given as mean ± SD or median (interquartile range). *Mean; £ 55% were H1N1pneumonia.