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Table 1 Definitions of multidrug-resistant bacteria monitored in the Zero Resistance program

From: Combatting resistance in intensive care: the multimodal approach of the Spanish ICU “Zero Resistance” program

Microorganism

Resistance marker

Gram-positive

 

Staphylococcus aureus

Methicillin (MRSA)

Enterococcus spp.

Vancomycin (VRE)

Gram-negative

 

Enterobacteriaceae

3rd generation cephalosporins (particularly ESBL-producing)

Carbapenems (particularly carbapenemase-producing)

Pseudomonas aeruginosa

≥ 3 antibiotic classes, including carbapenemsa, cephalosporinsb, piperacillin-tazobactam, flouroquinolones, aminoglycosidesd and colistin

Acinetobacter baumannii

Carbapenems

  1. aImipenem, meropenem or doripenem; bceftazidime or cefepime; cciprofloxacin or levofloxacin; gentamicin, tobramycin or amikacin. ESBL: extended spectrum beta-lactamase; MRSA: methicillin-resistant Staphylococcus aureus; VRE: vancomycin-resistant enterococcus.
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Critical Care

ISSN: 1364-8535