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Table 3 Summary of mortality data included in the meta-analysis

From: Incidence and outcome of inappropriate in-hospital empiric antibiotics for severe infection: a systematic review and meta-analysis

Reference Time of mortality assessment AAT mortality rate, % IAAT mortality rate, % P value
Kim et al. [21] 30 36.67 41.24 0.36
Kang et al. [12] 30 27.41 38.41 0.049
Micek et al. [33] IHM 17.83 30.67 0.018
Scarsi et al. [22] IHM 16.07 13.60 0.48
Marschall et al. [36] IHM 14.03 13.92 1.0
Shorr et al. [37] IHM 11.94 19.64 0.15
Rodríguez-Baño et al. [38] 30 18.18 24.24 0.3
Ammerlaan et al. [39] 30 25.00 21.27 NS
Erbay et al. [19] 30 39.53 65.00 0.011
Kumar et al. [40] IHM 48.00 89.70 <0.0001
Tseng et al. [41] IHM 35.44 50.00 OR 2.17 (1.4-3.38) 0.001
Micek et al. [42] IHM 36.40 51.68 <0.001
Paul et al. [43] 30 33.33 49.12 0.001
Joung et al. [44] 30 22.45 49.25 <0.0001
Suppli et al. [46] 30 20.55 40.00 0.009
Reisfeld et al. [47] 30 33.48 46.36 OR 1.4 (0.86-2.29) (NS)
Wilke et al. [48] IHM 14.02 26.32 0.021
Lye et al. [50] IHM 19.16 26.19 OR 0.67 (0.46-0.96) 0.03
Labelle et al. [54] IHM 51.38 68.30 <0.001
Frakking et al. [56] 30 18.82 20.41 NS
Tumbarello et al. [57] IHM 24.07 64.29 <0.001
  1. AAT, appropriate antibiotic therapy; IAAT, inappropriate antibiotic therapy; IHM, in-hospital mortality; OR, odds ratio; NS, not significant.