Optimizing mean arterial pressure in septic shock: a critical reappraisal of the literature

Table 3 Hemodynamic variables for mean arterial pressure targets of 65 and 85 mm Hg

Variables	References	Number of patients	65 mm Hg^a	85 mm Hg^a
Heart rate, beats per min	[16-22]	874	100 ± 11	101 ± 11
Cardiac index, L/min per m²	[16-21]	98	3.9 ± 1.9	4.3 ± 1.2
SvO₂ or ScvO₂, %	[16,17,19-21]	87	74 ± 2	75 ± 3
Lactate, mmol/L	[16-21]	98	2.3 ± 0.3	2.2 ± 0.4
Norepinephrine, μg/kg per min	[16-21]	874	0.47 ± 0.38	0.79 ± 0.52

^aWith respect to reference [19], values were derived from the calculation of mean values between 60 and 70 mm Hg for 65 mm Hg and between 80 and 90 mm Hg for 85 mm Hg. MAP, mean arterial pressure; ScvO₂, central venous oxygen saturation; SvO₂, mixed venous oxygen saturation.

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