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Table 3 Surgical and clinical characteristics at the time of the first, second and third repeat laparotomy for persistent peritonitis

From: Dynamic changes of microbial flora and therapeutic consequences in persistent peritonitis

  First repeat laparotomy Second repeat laparotomy Third repeat laparotomy P
n = 98 n = 54 n = 21
Time since previous surgery, days, mean ± SD 5 ± 5 6 ± 4 6 ± 5 0.32
Reasons for reoperation     
  Sepsis, n (%) 23 (23) 17 (32) 3 (16) 0.27
  Septic shock, n (%) 59 (60) 28 (55) 12 (63) 0.61
  Other reasons, n (%) 16 (16) 9 (17) 6 (29) 0.40
Intraoperative diagnosis, n (%)     
  Anastomotic leakage, n (%) 25 (26) 9 (17) 4 (21) 0.43
  Perforation or ischaemia, n (%) 17 (17) 14 (26) 4 (21) 0.44
  Purulent collection, n (%) 27 (28) 15 (28) 5 (26) 0.93
  Other causes, n (%) 8 (7) 10 (18) 2 (10) 0.15
  No cause, n (%) 21 (21) 6 (11) 6 (32) 0.15
Clinical characteristics at the time of reoperation     
  Temperature, °C, mean ± SD 38.2 ± 1.2 38.1 ± 1.4 38.0 ± 1.5 0.53
  WBCs, 109/L, mean ± SD 19.5 ± 11.2 20.7 ± 10.6 21.6 ± 10.5 0.65
  Creatinine (μmol/L) 159 ± 121 180 ± 129 202 ± 153 0.30
  SOFA score, mean ± SD 7 ± 4 8 ± 4 9 ± 3 0.33
  ≥2 organ dysfunctions, n (%) 45 (46) 27 (50) 11 (52) 0.81
  Haemodynamic failure1, n (%) 62 (63) 31 (57) 14 (67) 0.69
  Respiratory failure1, n (%) 38 (39) 22 (41) 5 (24) 0.37
  Renal failure1, n (%) 25 (26) 18 (33) 4 (21) 0.39
  1. 1Grade 3 or 4 of the SOFA score. WBCs, white blood cells; SOFA, sequential organ failure assessment.